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Tetrahydrofurfuryl alcohol ( CASNO:97-99-4 )
Identification and Related Records
- Tetrahydrofurfuryl alcohol
- CAS Registry number:
- Molecular Formula:
- Molecular Weight:
Chemical and Physical Properties
- Colorless to light yellow liquid
- Melting Point:
- Boiling Point:
- Refractive Index:
- Flash Point:
- Stable under normal temperatures and pressures.
- HS Code:
- Storage temp:
- Keep away from heat, sparks, and flame. Keep away from sources of ignition. Do not store in direct sunlight. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Store protected from moisture.
Safety and Handling
- Hazard Codes:
- Risk Statements:
- Safety Statements:
- Safety Information of Tetrahydrofurfuryl alcohol (CAS No.97-99-4):
Risk Statements: 36?
R36:Irritating to eyes.
Safety Statements: 39?
S39:Wear eye / face protection.
WGK Germany: 2
HS Code: 29321300
Hazardous Substances Data: 97-99-4(Hazardous Substances Data)
- I; II; III
- ??Tetrahydrofurfuryl alcohol (CAS No.97-99-4), it also can be called Tetrahydro-2-furanmethanol ; THFA? .
??Tetrahydrofurfuryl alcohol (CAS No.97-99-4)?is?a clear colorless liquid with a mild odor. its flash point 167°F, its?vapors are heavier than air,? it is denser than water and it?is soluble in water .?Tetrahydrofurfuryl alcohol (CAS No.97-99-4),inhalation or contact with it may irritate or burn skin and eyes. Fire may produce irritating, corrosive and/or toxic gases. Vapors may cause dizziness or suffocation. Runoff from fire control or dilution water may cause pollution.
??An organism tentatively identified as Ralstonia eutropha was isolated from enrichment cultures containing Tetrahydrofurfuryl alcohol (THFA) as the sole source of carbon and energy. The strain was able to tolerate up to 200 mM THFA in mineral salt medium. The degradation was initiated by an inducible ferricyanide-dependent alcohol dehydrogenase (ADH) which was detected in the soluble fraction of cell extracts. The enzyme catalyzed the oxidation of THFA to the corresponding tetrahydrofuran-2-carboxylic acid. Studies with n-pentanol as the substrate revealed that the corresponding aldehyde was released as a free intermediate. The enzyme was purified 211-fold to apparent homogeneity and could be identified as a quinohemoprotein containing one pyrroloquinoline quinone and one covalently bound heme c per monomer. It was a monomer of 73 kDa and had an isoelectric point of 9.1. A broad substrate spectrum was obtained for the enzyme, which converted different primary alcohols, starting from C2 compounds, secondary alcohols, diols, polyethylene glycol 6000, and aldehydes, including formaldehyde. A sequence identity of 65% with a quinohemoprotein ADH from Comamonas testosteroni was found by comparing 36 N-terminal amino acids. The ferricyanide-dependent ADH activity was induced during growth on different alcohols except ethanol. In addition to this activity, an NAD-dependent ADH was present depending on the alcohol used as the carbon source.
- ? Tetrahydrofurfuryl alcohol is?reported in EPA TSCA Inventory.
Use and Manufacturing
- Solvent for fats, waxes, resins, in organic synthesis.
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