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Calcium lactate ( CASNO:814-80-2 )

Identification and Related Records
Name:
Calcium lactate
CAS Registry number:
814-80-2
Synonyms:
Lacticacid, calcium salt (2:1) (8CI)
Calcium DL-lactate
Propanoicacid, 2-hydroxy-, calcium salt (2:1)
Calphosan
Conclyte Ca
E 327
L-Cal
Pationic 1230
Pationic 1240
Prequist Powder
Puracal PP/FCC
Puracal PP/USP
Tokal
Calcium Lactate FCC/USP
EINECS(EC#):
212-406-7
Molecular Formula:
C6H10CaO6
Molecular Weight:
218.22
Inchi:
InChI=1/2C3H6O3.Ca/c2*1-2(4)3(5)6;/h2*2,4H,1H3,(H,5,6);/q;;+2/p-2
Canonical SMILES:
CC(C(=O)[O-])O.CC(C(=O)[O-])O.[Ca+2]
Chemical and Physical Properties
Appearance:
White powder.
Boiling Point:
227.6 °C at 760 mmHg
Flash Point:
109.9 °C
Solubilities:
Soluble
Color/Form:
White, crystalline powder
Stability:
Stable.
Storage temp:
Keep tightly closed in a cool place in a tightly closed container.
Spectral properties:
INDEX OF REFRACTION: 1.470 (ALPHA), 1.510 (GAMMA); ELONGATION: +, EXTINCTION PARALLEL
Computed Properties:
Molecular Weight:218.218 [g/mol]
Molecular Formula:C6H10CaO6
H-Bond Donor:2
H-Bond Acceptor:6
Rotatable Bond Count:0
Exact Mass:218.010329
MonoIsotopic Mass:218.010329
Topological Polar Surface Area:121
Heavy Atom Count:13
Formal Charge:0
Complexity:53.5
Isotope Atom Count:0
Defined Atom Stereocenter Count:0
Undefined Atom Stereocenter Count:2
Defined Bond Stereocenter Count:0
Undefined Bond Stereocenter Count:0
Covalently-Bonded Unit Count:3
Safety and Handling
Risk Statements:
R36/37/38
Safety Statements:
26-36/37/39
Safety:
Risk Statements: 36/37/38?
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 26-36/37/39?
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.?
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.
TSCA Yes
Formulations/Preparations:
CALCIUM LACTATE USP; POWDER USP, TABLETS USP, 325 MG (42.25 MG CALCIUM), & 650 MG (84.5 MG CALCIUM)
Commercial prepn usually contains about 25% water, and on the anhydrous basis it is at least 98% pure.
GRADES: NF; FCC.
Exposure Standards and Regulations:
Substance added directly to human food affirmed as generally recognized as safe (GRAS).
Calcium lactate used as a general purpose food additive is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
Specification:

Safety Statements:26-36/37/39
26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
36/37/39:Wear suitable protective clothing, gloves and eye/face protection
Disposal Methods:
SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.
Use and Manufacturing
Use and Manufacturing:
Methods of Manufacturing

FERMENTATION OF CARBOHYDRATES TO LACTIC ACID, WITH PH CONTROLLED BY CALCIUM CARBONATE; REACTION OF LACTIC ACID WITH CALCIUM CARBONATE OR CALCIUM HYDROXIDE
... Commercially by neutralization of lactic acid, from fermentation of dextrose, molasses, starch, sugar or whey, with calcium carbonate.
U.S. Imports

(1972) 6.11X10+8 GRAMS (LACTIC ACID)
(1973) 6.25X10+8 GRAMS (LACTIC ACID)
U.S. Production

(1972) 8.63X10+8 GRAMS (ALL LACTIC ACID SALTS)
(1975) PROBABLY GREATER THAN 4.54X10+5 GRAMS
Usage:
Food additive.
Biomedical Effects and Toxicity
Therapeutic Uses:
EXPTL USE: ORAL ADMIN OF CALCIUM LACTATE (7.7 G) LOWERED PLASMA PARATHYROID HORMONE BY 40-43% & DECR URINARY EXCRETION OF CYCLIC ADENOSINE MONOPHOSPHATE BY 30-54% IN SKELETAL-TYPE HYPERPARATHYROIDISM BUT NOT IN OTHER TYPES OR IN CONTROLS.
EXPTL USE: HIGH DOSES OF ORAL CALCIUM LACTATE DECR URINARY CYCLIC ADENOSINE MONOPHOSPHATE EXCRETION IN BORDERLINE CASES OF UROLITHIC AND CHEM HYPERPARATHYROIDISM.
May be used to treat mild hypocalcemia and for maintenance therapy. /From table/
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