CAS Search
Related Chemical Product
Buy Chemical NO: 7491-74-9
  • Urgent Purchase CAS NO.:7491-74-9
  • Please post your buying leads! Our suppliers will contact you later!
  • For suppliers to better understand your request, enter more info here.

* Product Name:
CAS No.:
* Quantity:
 
 Metric Ton     Kilogram    Gram    Pound
* Valid For:
 5 Days    15    1 Month    3 Month    6 Month    1 Year
* Description:

Max 2000 characters.  Please enter detailed description for the product.
* Email:
 

Piracetam ( CASNO:7491-74-9 )

Identification and Related Records
Name:
Piracetam
CAS Registry number:
7491-74-9
Iupac name:
2-(2-oxopyrrolidin-1-yl)acetamide
Synonyms:
Myocalm
Neuracetam
Nootobril
Nootobryl
Nootron
Nootrop
Nootropil
Nootropyl
Normabrain
Norzetam
(2-Oxopyrrolidino)acetamide
2-(2-Oxopyrrolidin-1-yl)acetamide
2-Ketopyrrolidine-1-acetamide
2-Oxo-1-pyrrolidineacetamide
2-Oxo-1-pyrrolidinylacetamide
2-Pyrrolidinoneacetamide
2-Pyrrolidoneacetamide
Avigilen
Axonyl
Cerebroforte
Cl 781
Encetrop
Euvifor
Gabacet
Genogris
Geram
EINECS(EC#):
231-312-7
Molecular Formula:
C6H10N2O2
Molecular Weight:
142.16
Inchi:
InChI=1/C6H10N2O2/c7-5(9)4-8-3-1-2-6(8)10/h1-4H2,(H2,7,9)
InChIKey:
GMZVRMREEHBGGF-UHFFFAOYSA-N
Canonical SMILES:
C1CC(=O)N(C1)CC(=O)N
Chemical and Physical Properties
Density:
1.239 g/cm3
Melting Point:
151-152 °C
Boiling Point:
408.3 °C at 760 mmHg
Refractive Index:
1.523
Flash Point:
200.8 °C
Solubilities:
Very soluble
Color/Form:
Crystals from isopropanol
Stability:
Stable at normal temperatures and pressures.
Storage temp:
Keep tightly closed.
Computed Properties:
Molecular Weight:142.1558 [g/mol]
Molecular Formula:C6H10N2O2
XLogP3-AA:-1.3
H-Bond Donor:1
H-Bond Acceptor:2
Rotatable Bond Count:2
Tautomer Count:6
Exact Mass:142.074228
MonoIsotopic Mass:142.074228
Topological Polar Surface Area:63.4
Heavy Atom Count:10
Formal Charge:0
Complexity:167
Isotope Atom Count:0
Defined Atom Stereocenter Count:0
Undefined Atom Stereocenter Count:0
Defined Bond Stereocenter Count:0
Undefined Bond Stereocenter Count:0
Covalently-Bonded Unit Count:1
Feature 3D Acceptor Count:2
Feature 3D Donor Count:1
Feature 3D Ring Count:1
Effective Rotor Count:2.8
Conformer Sampling RMSD:0.6
CID Conformer Count:5
Safety and Handling
Hazard Codes:
Xi: Irritant;
Risk Statements:
R36/37/38
Safety Statements:
26-37/39
Safety:
Hazard Codes:?IrritantXi
Risk Statements: 36/37/38?
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 26-37/39?
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.?
S37/39:Wear suitable gloves and eye/face protection.
WGK Germany: 2
RTECS: UX9660500
Formulations/Preparations:
Nootropil 800 and 1200 mg Tablets: Polyethylene glycol 6000, Colloidal anhydrous silica, Magnesium stearate, Methocel, Titanium dioxide (E171), Polyethylene glycol 400. Nootropil Solution 33%: Glycerol, Methyl parahydroxybenzoate, Propyl parahydroxybenzoate, Sodium acetate, Acetic acid, Purified water
Avigilen
Axonyl
Ciclofalina
Cerebroforte
Encetrop
Gabacet
Genogris
Geram
Nootrop
Nootropil
Nootropyl
Norzetam
Normabrain
Piracebral
Pirroxil
Pyramem
Piracetrop
Sinapsan
Specification:
?Piracetam , its cas register number is 7491-74-9. It also can be called 1-Acetamido-2-pyrrolidinone ; 2-Ketopyrrolidine-1-ylacetamide ; 2-Oxo-1-pyrrolidineacetamide ; 2-Oxo-pyrrolidin-1-ylacetamide ; 2-Oxo-pyrrolidine acetamide ; 1-Pyrrolidineacetamide, 2-oxo- .It is?very soluble?in water.
Octanol/Water Partition Coefficient:
log Kow = -1.54
Disposal Methods:
SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.
Use and Manufacturing
Use and Manufacturing:
Methods of Manufacturing

... Prepared by condensing 2-pyrrolidinone with ethyl chloroacetate in the presence of a metal hydride and then converting the ester into an amide with ammonia.
Prepn: H. Morren, NL 6509994; eidem, US 3459738 (1966, 1969 both to U.C.B)
Usage:
Medication.
Biomedical Effects and Toxicity
Biological Activity:
Nootropic that displays cognitive enhancing properties. Proposed to enhance neurotransmission via modulation of ion flux; potentiates Na + influx through AMPA receptors. Facilitates efficiency of cholinergic neurotransmission at muscarinic receptors.
Pharmacological Action:
- Drugs intended to prevent damage to the brain or spinal cord from ischemia, stroke, convulsions, or trauma. Some must be administered before the event, but others may be effective for some time after. They act by a variety of mechanisms, but often directly or indirectly minimize the damage produced by endogenous excitatory amino acids.
- Drugs used to specifically facilitate learning or memory, particularly to prevent the cognitive deficits associated with dementias. These drugs act by a variety of mechanisms. While no potent nootropic drugs have yet been accepted for general use, several are being actively investigated.
Therapeutic Uses:
/Investigators/ report on a 30-year-old patient with advanced cerebellar degeneration due to sickle cell amemia 2. He presented with severe myoclonus, which was resistant to conventional therapy and dramatically improved after administration of 12-18 g/day piracetam. Piracetam may be considered in the treatment of refractory myoclonus in spinocerebellar degenerations. [De Rosa A et al; Mov Disord 21 (1): 116-8 (2006)]
Biomedical Effects and Toxicity:
Piracetam is rapidly and almost completely absorbed. Peak plasma levels are reached within 1.5 hours after administration. The extent of oral bioavailability, assessed from the Area Under Curve (AUC), is close to 100% for capsules, tablets and solution.
Peak levels and AUC are proportional to the dose given. The volume of distribution of piracetam is 0.7 L/kg, and ... Clearance of the compound is dependent on the renal creatinine clearance and would be expected to diminish with renal insufficiency.
Piracetam is excreted in human breast milk.
Piracetam crosses the blood-brain and the placental barrier and diffuses across membranes used in renal dialysis.
Piracetam is excreted almost completely in urine and the fraction of the dose excreted in urine is independent of the dose given.
Chemical Company
Bella Furniture Co.,Ltd:
Bella Furniture Co.,Ltd located in the "art of China's top 10 most dynamic cities" - Wenzhou,Website:http://www.bellacasafromchina.com, BELLA CASA, a special brand of classical Italy style furniture, has committed to the people design and manufacture of furniture systems for the whole home, from the living and dining areas through to the bedroom. According to the modern development trend, the industry of furniture is changing constantly. At the age of edge of this extinct traditional and craft art, BELLA CASA still persists in unique craft skill and lasting elegant style, have discarded the general skillful decorations of line in great numbers of furniture, adopts the plain surface, assists it with the succinct straight line, the curve and some classical art languages. Not to be the bigges 
Chengdu Runde Pharmaceutical Co., Ltd:
Chengdu Runde Pharmaceutical Co., Ltd. is really a GMP factory focused on removing, Synthesizing and developing active plant monomer, active pharmaceutical intermediates and chemicals from Citrus Extracts and Derivitives. we extract and manufacture a large number of items from citrus aurantium seed, for example Diosmin, Naringin, naringenin,Hesperidin Methyl Chalcone, Eriocitrin and ETC.With superior quality and Good after-sales services, our items are offered well in lots of other nations and regions, like the U . s . States, Europe, Japan and India, and win extensive praises from clients.  
Hangzhou Oil and Fat Chemical Co., Ltd.:
 
东莞市天翊网络科技有限公司:
 
sunnyjoint chemicals:
Shenyang Sunnyjoint Chemicals co., Ltd, is really a professional manufacturer and supplier of chemicals for rubber processing industry. To learn more, Pl kindly login website of world wide web.sunnyjoint.com 
hebei wanye chemical stock co.,ltd:
He bei wanye chemical stock co.,ltd restructured in the year 2006 established greater than two decades Ⅰ ears producttion history of chemicals .which is one of the largest chemcial factory in hebei province .The organization is situated in the feet from the beautiful taihang mountain tops, the visitors are very convenient.Ⅰ Ⅰ Ⅰ Ⅰ Hebei wanye chemical stock co.,ltd is a public company which mainly engages in the development , production and selling of phosphate chemicals and other chemcial items. The new selling items include: sodium tripolyphosphate (stpp) ,sodium laurylether sulfate ( SLES) ,sodium lauryl sulfate (SLS) ,sodium hexametaphoshpate (SHMP) ,sodium gluconate ,sulfamic acid , caustic soda (flakes &pearls ), soda ash ( light & dense ) titanium dioxide and so on . we've  
CandM Inter-cooperation Limited:
CandM Inter-cooperation Limited is a professional manufacturer and exporter of all kinds of iphone & samsung in China,Website:http://www.cm-accessoriestech.com, with well-equipped testing and production facilities and strong technical force. We are proud of our skilled workers and enthusiastic staff. We always guarantee reasonable prices, good quality and punctual delivery. Therefore, through all these years' efforts, we have developed very quickly and our products are widely recognized and trusted by users and can meet continuously developing economic and social needs. Well inspected before shipment. Strict quality control is implemented in all aspects of our operations to meet the high standards of top-tier customers. As a result of our high quality products and outstanding customer se 
SHAANXI XIYUE PHARMACEUTICAL CO.,LTD:
 
BAODING KAIYUE CHEMICAL CO., LTD BD:
 
suzhou mro safety equipment co,.ltd24738:
RO COMPANY is a global multi-business group with its head office based in Suzhou, China. Our core business consists of MRO, lab, Medical technology, Engineering Business & PE. After 8 years development MRO COMPANY has turned into a leading company in MRO, Lab & Medical equipments field. Nearly all top global 500 and well-known Chinese businesses have grown to be important clients to all of us. And during this time period of your time we're been successful within the buyout of the couple of well-known brands, MRO Clients are a business with increased than50 individuals our sourcing team who analyses every supplier carefully while developing items to ensure that we are able to provide top quality items with huge discounts to the esteemed clients. We have a powerful financial background and s 
TIANJIN HUIHONG INDUSTRIAL CO.,LTD:
Tin Ingot antimony ingot Antimony trioxide Magnesium Ingot Lead ingot Manganese Metal Silicon Calcium Ferro Molybdenum Ferro Manganese Silicon Manganese Silicon metal Ferro silicon Tellurium selenium Lead antimony alloy Babbitt metal Cerium metal Misch metal 
NANTONG KINGWAY COMPLEX MATERIAL CO.,LTD:
Nantong Kingway Complex Material CO., Ltd (Nantong Hekway Building Material CO.,Website:http://www.chinahousewrap.com, Ltd) is a leading professional manufacturer in China, which locates in Haian State-grade Development Zone, Jiangsu Province.?We specialize in nonwoven products, film lamination, roofing materials, disposable medical products, packaging materials and so on. Our main products: Nonwoven fabric , and manufactured products,Film or foil laminated products,Roofing membrane, flooring underlay,PE woven fabric, PE tarpaulin, vapor barrier,Greenhouse We not only have first-class processing line, but have first-grade quality management. We have been qualified by ISO9001 (quality) and CE, this system can supply active way to guarantee the quality. We have exported to many countries, su 
LIAOYANG TENGYUAN FOOD ADDITIVE FACTORY:
 
Vansbon Co., Ltd:
  Vansbon is focused on supply silicone scar sheet, SCAR GEL and scar care items. Our silicone scar sheet is really a unique product for enhancing scars. It's an advanced type of silicone within an adhesive gel sheet, that has been broadly utilized by skin doctors, surgeons and doctors in lowering old and new red and elevated scars by flattening, diminishing and conditioning.  Our silicone scar sheets happen to be released to United kingdom, USA, Norwegian, Hongkong, Japan, Poultry, Netherlands, Denmark, and ETC.  The primary items include: Silicone scar sheet, silicone gel strip, medical silicone gel, surgical scar caring, soft silicone scar therapy, scar repair silicone, silicone sheet for C-sections, self-adhesive silicone sheet, scar treatment s 
Wuhan Yuancheng Pharmaceutical Co.,Ltd:
 
Yantai Relyon Chemical Technology Co.,Ltd.:
 
Hong Kong Biotek Chemicals Co., Ltd:
 
Biochemicals Co., Ltd:
Situated in east of China, famouse because of its worldwide business and convenient seaport.Mainly cope with export of pharmaceutical raw material, intermediate, food additive, ETC. we're searching toward become the perfect another professional, sincere and reliable partner. 
VU Electronic Co.,Ltd:
VU Electronic Co.,Ltd,Website:http://www.szvutechs.com, committed to new and fashionable home theater system, audio and video products development, manufacturing, sales. "VU" means "Very Unique". It is gathering a group of ambitious, passionate young people to build a powerful team which has international view and innovation spirit. To make your digital life be more special . VU has an excellent & professional R&D team. Every engineer in VU has 5-8 years work experience, including software, hardware and other fields. Products cover the HDMI distribution, switching, transformation, matrix, extend, decoding, etc., Our products are a wide range of application for HDTV, digital set-top box, DVD, projector, multimedia conference room application solutions, command center application solutions 
Xingyang Yuxin Recreation Equipment Factory: