CAS Search
Related Chemical Product
Buy Chemical NO: 7491-74-9
  • Urgent Purchase CAS NO.:7491-74-9
  • Please post your buying leads! Our suppliers will contact you later!
  • For suppliers to better understand your request, enter more info here.

* Product Name:
CAS No.:
* Quantity:
 Metric Ton     Kilogram    Gram    Pound
* Valid For:
 5 Days    15    1 Month    3 Month    6 Month    1 Year
* Description:

Max 2000 characters.  Please enter detailed description for the product.
* Email:

Piracetam ( CASNO:7491-74-9 )

Identification and Related Records
CAS Registry number:
Iupac name:
Cl 781
Molecular Formula:
Molecular Weight:
Canonical SMILES:
Chemical and Physical Properties
1.239 g/cm3
Melting Point:
151-152 °C
Boiling Point:
408.3 °C at 760 mmHg
Refractive Index:
Flash Point:
200.8 °C
Very soluble
Crystals from isopropanol
Stable at normal temperatures and pressures.
Storage temp:
Keep tightly closed.
Computed Properties:
Molecular Weight:142.1558 [g/mol]
Molecular Formula:C6H10N2O2
H-Bond Donor:1
H-Bond Acceptor:2
Rotatable Bond Count:2
Tautomer Count:6
Exact Mass:142.074228
MonoIsotopic Mass:142.074228
Topological Polar Surface Area:63.4
Heavy Atom Count:10
Formal Charge:0
Isotope Atom Count:0
Defined Atom Stereocenter Count:0
Undefined Atom Stereocenter Count:0
Defined Bond Stereocenter Count:0
Undefined Bond Stereocenter Count:0
Covalently-Bonded Unit Count:1
Feature 3D Acceptor Count:2
Feature 3D Donor Count:1
Feature 3D Ring Count:1
Effective Rotor Count:2.8
Conformer Sampling RMSD:0.6
CID Conformer Count:5
Safety and Handling
Hazard Codes:
Xi: Irritant;
Risk Statements:
Safety Statements:
Hazard Codes:?IrritantXi
Risk Statements: 36/37/38?
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 26-37/39?
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.?
S37/39:Wear suitable gloves and eye/face protection.
WGK Germany: 2
RTECS: UX9660500
Nootropil 800 and 1200 mg Tablets: Polyethylene glycol 6000, Colloidal anhydrous silica, Magnesium stearate, Methocel, Titanium dioxide (E171), Polyethylene glycol 400. Nootropil Solution 33%: Glycerol, Methyl parahydroxybenzoate, Propyl parahydroxybenzoate, Sodium acetate, Acetic acid, Purified water
?Piracetam , its cas register number is 7491-74-9. It also can be called 1-Acetamido-2-pyrrolidinone ; 2-Ketopyrrolidine-1-ylacetamide ; 2-Oxo-1-pyrrolidineacetamide ; 2-Oxo-pyrrolidin-1-ylacetamide ; 2-Oxo-pyrrolidine acetamide ; 1-Pyrrolidineacetamide, 2-oxo- .It is?very soluble?in water.
Octanol/Water Partition Coefficient:
log Kow = -1.54
Disposal Methods:
SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.
Use and Manufacturing
Use and Manufacturing:
Methods of Manufacturing

... Prepared by condensing 2-pyrrolidinone with ethyl chloroacetate in the presence of a metal hydride and then converting the ester into an amide with ammonia.
Prepn: H. Morren, NL 6509994; eidem, US 3459738 (1966, 1969 both to U.C.B)
Biomedical Effects and Toxicity
Biological Activity:
Nootropic that displays cognitive enhancing properties. Proposed to enhance neurotransmission via modulation of ion flux; potentiates Na + influx through AMPA receptors. Facilitates efficiency of cholinergic neurotransmission at muscarinic receptors.
Pharmacological Action:
- Drugs intended to prevent damage to the brain or spinal cord from ischemia, stroke, convulsions, or trauma. Some must be administered before the event, but others may be effective for some time after. They act by a variety of mechanisms, but often directly or indirectly minimize the damage produced by endogenous excitatory amino acids.
- Drugs used to specifically facilitate learning or memory, particularly to prevent the cognitive deficits associated with dementias. These drugs act by a variety of mechanisms. While no potent nootropic drugs have yet been accepted for general use, several are being actively investigated.
Therapeutic Uses:
/Investigators/ report on a 30-year-old patient with advanced cerebellar degeneration due to sickle cell amemia 2. He presented with severe myoclonus, which was resistant to conventional therapy and dramatically improved after administration of 12-18 g/day piracetam. Piracetam may be considered in the treatment of refractory myoclonus in spinocerebellar degenerations. [De Rosa A et al; Mov Disord 21 (1): 116-8 (2006)]
Biomedical Effects and Toxicity:
Piracetam is rapidly and almost completely absorbed. Peak plasma levels are reached within 1.5 hours after administration. The extent of oral bioavailability, assessed from the Area Under Curve (AUC), is close to 100% for capsules, tablets and solution.
Peak levels and AUC are proportional to the dose given. The volume of distribution of piracetam is 0.7 L/kg, and ... Clearance of the compound is dependent on the renal creatinine clearance and would be expected to diminish with renal insufficiency.
Piracetam is excreted in human breast milk.
Piracetam crosses the blood-brain and the placental barrier and diffuses across membranes used in renal dialysis.
Piracetam is excreted almost completely in urine and the fraction of the dose excreted in urine is independent of the dose given.
Chemical Company
sve chem:
World Precise Machinery (Nanjing) Co., Ltd:
WORLD PRESS is professional manufacturer of power press machine since 1953,Website:, can supply press machine capacities from 6.3 ton to 2000 ton including C frame press (gap frame press), H frame press (straight side press), single crank press, double crank press with CE approved. Has more than?10,000?workers,?666,000?㎡?factory?workshop,? are supplier?of?BMW,?Volkswagen,?Hyundai?factory in China.? 
Zhejiang Kinglyuan Pharmaceutical Company Limited:
Zhejiang Kinglyuan Pharmaceutical Company Limited is situated in Hangzhou Bay, that was stated that “Up above there's Paradise, lower here there's Suzhou and Hangzhou”, in Zhejiang Province. Listed here are beautiful scenery, enjoyable climate and good physical atmosphere. There exists a total section of 160,000 square meters, a complete resource of RMB 260 million and a complete staff of 560, 22 who have senior title of technical publish and 62% who have medium grade title of technical publish and related technical background. We've branch companies of Kinglyuan Research and development center, Shangyu Shengda Biochemical Company Limited and Zhejiang Newgen Pharmaceutical Distribution Company. After greater than ten-year development, the organization is becoming an exciting-around pharmac 
Jiaxing Leeway Energy& Technology Co.,Ltd:
Jiaxing Leeway company ,Website:,located in Jiaxing city ,Zhejiang province ,is specialized in manufacturing and exporting all kinds of lighting product .including LED lamp ,energy saving lamp ,halogen bulb and other special bulbs . We are selling the product to Europe ,South America ,Middle east countries and Africa . By supplying stable quality goods and excellect trade service , we win the confidence from different customers and have established long-term business relationship with them. We have strong QC team ,who is applying meticulous quality checking for every shipment in the factory . Checks are performed on semifinished items ,finished product and packages .We must ensure that every product to our customer shall be perfect without any performance fault  
Globe Chemie:
Zhejiang Tianxin Pharmaceutical Co.,Ltd:
Yiwu Shiyi Jewelry Co.,Ltd:
“We?think?our?products?will?give?you?an?edge?over?your?competitors.” Shiyi Jewelry?Co.,Ltd?is?a?manufacturer?specialized?in?OEM/ODM?service?for?Jewelry.?Our?main?product?is Crystal jewelry,Website:,?especially?Austrian Crystal Necklace Jewelry.?We?have?been?known?as?the?first?DIY-Crystal?base?in?China. Our?company?has?about?7?years'?experience?in?Jewelry.?We?believe?our?professional?knowledge?can?make?our?cooperation?and?communication?easy?and?fruitful.?We?will?try?our?best?to?make?you?satisfied?with?our?products?and?services.?We?not?only?supply?the?existing?products,?but?also?can?produce?new?products?with?customers. We?have?factory?located?in?Yiwu.?We?will?provide?customers?with?the?latest?products,?the?most?competitive?prices?and?professional?after-sales?servi 
Lords Biotech is really a dynamic and expertly handled company that's involved in the manufacturing of specialty Bromine, Lithium and Cycloalkane compounds that are used in neuro-scientific Pharma, agrochemicals, refrigeration, Tastes and specialty solvents. Lords Biotech began about ten years ago by a skilled and highly qualified technocrat who built the business round the concepts of honesty, integrity, competency, transperency and plan to make worldclass eco-friendly items. We love strong loyalty from your clients and their consistent annual contracts encouraged us to improve our capacity every year. We've added more innovative items to fulfill the ever growing global needs.Our clients are the greatest MNCs around the globe to small start-ups. We made the decision to export our it 
Hangzhou Imee Printing co., LTD:
IMEE is a professional booklet printing & packaing box and bags printing company and factory in China. We are specializing in booklet printing,Website:, brochure printing, catalog printing, box printing, bag printing, and so on. We also supply all kinds of office products and business gifts, maintain good business solutions for customers. These products are been delivered to Europe, United States, Oceanica, Asia, ?Africa etc. countries. We are expanding more cooperation partners all over the world. 
Shandong Daguang Industrial Limited:
Tianjin wurui chemical I&E Co.,LTD:
Xi'an Keen-source Biotechnology Co.,Ltd:
Fuclear Sci&Tec(Suzhou)Co.,Ltd:
Longze Magnet Electronic Co.,Ltd:
Ongze Magnet Electronic Co.,Ltd started in 1999, may be the batch manufacture of several types of magnet material,Professional manufacturer of magnet materials. The primary items in our company are all sorts of ndfeb magnets, Ferrite Magnets, Magnet, Plastic Magnet, rubber magnets, items are broadly utilized in electronic industry, mining and metallurgy, treatment, industrial automation, oil energy industry, civil industry and the like.Longze Magnet Electronic continues to be sticking towards the "quality first, status first", to science and Technology Innovation, enhancing the standard from the product. Company manufacture of rotor magnet quality is great, Since 1999, is just about the major domestic and worldwide marine items company, automatic washers, the primary supplier from the pump 
hunan tianwang tea industry co., ltd:
Unan Tianwang Tea Industry Co., Ltd. stems from Hunan Xinghuo Tea Industry Co., Ltd., that was founded in 1994. We've passed ISO 9001:2008 certificate and like a leading enterprise from the Farming Industrialization of Hunan Province. Tianwang is principally devoted to fabricate and supply Top quality tea. Our Philosophy is “Reliable Quality, fair prices, honest cooperation and professional service.” The knowledgeable person in Tianwang Tea has extensive management experience and seem understanding of tea industry.Our primary items are Eco-friendly tea, black tea and dark tea, Also we are able to supply perfumed tea, oolong tea benefits, pu'er tea, white-colored tea etc. Through 19 years developing, we can now supply 500 Ton monthly. Meanwhile we're Top Ten credit enterprise in Hunan tea  
Shandong Bechem Chemicals Co., Ltd:
Taizhou wire EDM-Chengdu Office:
Tianjin YouJu Technology Co., really a professional supplier and distributor of APIs/pharmaceutical intermediates,and chicken feed supplements,Fertilizer Chemicals,Animal Feed Grade,conveying items with higher quality and huge discounts.Hope cooperate along with you!  
Guangzhou Jiangyan Chemical Co.,Ltd:
Shaanxi Weinan Huifeng Chemical Industry Co.,Ltd.:
We are situated within the biggest city in East Shaanxi province. It likes a good geographic position and convenient transportation for Lengthy hai railway, Xi tong expressway and310 condition road meet here. Our organization was initially founded as Weinan Chemical Plant and restructured into "shaanxi province weinan huifeng chemical industry co., Ltd" in 1997. We now have 126 employees and a yearly production value in excess of RMB 20 million. our items, greater than ten kinds, are offered in your own home and abroad. Insisting around the operating philosophy of "quality may be the existence, credit may be the basis", Huifeng Chemical Industry Co.,Ltd., involved in producing fine chemicals and drug intermediates, has turned into a quality product manufacturer reliable by clients......