- Urgent Purchase CAS NO.:63-05-8
- Please post your buying leads! Our suppliers will contact you later!
- For suppliers to better understand your request, enter more info here.
Androst-4-ene-3,17-dione ( CASNO:63-05-8 )
Identification and Related Records
- CAS Registry number:
- Molecular Formula:
- Molecular Weight:
- Canonical SMILES:
- Isomers smiles:
Chemical and Physical Properties
- white to off-white solid
- 1.11 g/cm3
- Melting Point:
- Boiling Point:
- 431.4 oC at 760 mmHg
- Refractive Index:
- Flash Point:
- 161.1 oC
- Dimorphous. Needles from acetone; crystals from hexane
- Stable at normal temperatures and pressures.
- HS Code:
- Storage temp:
- Keep tightly closed.
- Spectral properties:
- Specific optical rotation = +191 deg C/D at 30 deg C (alcohol)
UV max = 235 nm
MASS: 62023 (NIST/EPA/MSDC Mass Spectral Data Base, 1990 Version)
IR: 5443 (Coblentz Society Spectral Collection)
UV: 7-847 (Phillip et al., Organic Electronic Spectral Data, John Wiley & Sons, New York)
1H NMR: 9959 (Sadler Research Laboratories Spectral Collection)
13 C NMR: 482 (Johnson and Jankowski, Carbon 13 NMR Spectra, John Wiley & Sons, New York)
- Computed Properties:
- Molecular Weight:286.40854 [g/mol]
Rotatable Bond Count:0
Topological Polar Surface Area:34.1
Heavy Atom Count:21
Isotope Atom Count:0
Defined Atom Stereocenter Count:5
Undefined Atom Stereocenter Count:0
Defined Bond Stereocenter Count:0
Undefined Bond Stereocenter Count:0
Covalently-Bonded Unit Count:1
Feature 3D Acceptor Count:2
Feature 3D Ring Count:4
Effective Rotor Count:1.6
Conformer Sampling RMSD:0.6
CID Conformer Count:1
Safety and Handling
- Hazard Codes:
- Risk Statements:
- Safety Statements:
- An experimental teratogen. Other experimental reproductive effects. Questionable carcinogen with experimental tumorigenic data. When heated to decomposition it emits acrid smoke and irritating fumes.
White to Off-White Solid
usageEng:Testosterone precursor and metabolite with androgenic activity. Controlled substance (anabolic sterid)
22:Do not breathe dust
24/25:Avoid contact with skin and eyes
36:Wear suitable protective clothing
- Octanol/Water Partition Coefficient:
- log Kow = 2.75
- Disposal Methods:
- SRP: The most favorable course of action is to use an alternative chemical product with less inherent propensity for occupational exposure or environmental contamination. Recycle any unused portion of the material for its approved use or return it to the manufacturer or supplier. Ultimate disposal of the chemical must consider: the material's impact on air quality; potential migration in soil or water; effects on animal, aquatic, and plant life; and conformance with environmental and public health regulations.
Use and Manufacturing
- Use and Manufacturing:
- Methods of Manufacturing
Preparation: ... Isolation from adrenal cortex.
- Testosterone precursor and metabolite with androgenic activity. Controlled substance (anabolic sterid)
Biomedical Effects and Toxicity
- Therapeutic Uses:
- Testosterone precursor and metabolite with androgenic activity. Controlled substance (anabolic sterid)
- Biomedical Effects and Toxicity:
- It is not known whether anabolic steroids are distributed into breast milk. /Anabolic Steroids/
Environmental Fate and Exposure Potential
- Environmental Fate/Exposure Summary:
- TERRESTRIAL FATE: Based on a classification scheme(1), an estimated Koc value of 750(SRC), determined from a log Kow of 2.75(2)and a regression-derived equation(3), indicates that androstenedione is expected to have moderate mobility in soil(SRC). Volatilization of androstenedione from moist soil surfaces is not expected to be an important fate process(SRC) given an estimated Henry's Law constant of 3.7X10-8 atm-cu m/mole(SRC), using a fragment constant estimation method(4). Androstenedione is not expected to volatilize from dry soil surfaces(SRC) based upon an estimated vapor pressure of 1.8X10-6 mm Hg(SRC), determined from a fragment constant method(5). No biodegradation data were available(SRC, 2005).
AQUATIC FATE: Based on a classification scheme(1), an estimated Koc value of 750(SRC), determined from a log Kow of 2.75(2) and a regression-derived equation(3), indicates that androstenedione is expected to adsorb to suspended solids and sediment(SRC). Volatilization from water surfaces is not expected(3) based upon an estimated Henry's Law constant of 3.7X10-8 atm-cu m/mole(SRC), developed using a fragment constant estimation method(4). According to a classification scheme(5), an estimated BCF of 26(SRC), from its log Kow(2) and a regression-derived equation(6), suggests the potential for bioconcentration in aquatic organisms is low(SRC). No biodegradation data were available(SRC, 2005).
ATMOSPHERIC FATE: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), androstenedione, which has an estimated vapor pressure of 1.8X10-6 mm Hg at 25 deg C(SRC), determined from a fragment constant method(2), will exist in both the vapor and particulate phases in the ambient atmosphere. Vapor-phase androstenedione is degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals(SRC); the half-life for this reaction in air is estimated to be 3.5 hours(SRC), calculated from its rate constant of 1.1X10-10 cu cm/molecule-sec at 25 deg C(SRC) that was derived using a structure estimation method(3). Particulate-phase androstenedione may be removed from the air by wet and dry deposition(SRC). Androstenedione does not absorb light at wavelenghts >290 nm(4) and therefore is not expected to be susceptible to direct photolysis(SRC).
- Guangzhou dianchuang hardware seating Co., Ltd:
- Guangzhou DianChuang Hardware Seating Co., Ltd. is one of the leading manufacturers in South China,Website:http://www.chinacinemaseating.com, we dedicated to provide the market with the best quality products with reasonable price, our mission is provide the high quality for cinema seating, auditorium seating, lecture hall seating and VIP home theater seating to all our clients, combing with our best customer service, promote lead time and customized service, we will be your one of the best solutions in pubic seating and home theater solution. DianChuang Seating is the company that you can reply on!
- Sundent Pharm Group:
- Sundent Pharm Group (together with its subsidiaries,Website:http://www.sundentpharm.com, the Group”) is one of the largest comprehensive manufacturing, marketing, promotion and channel management service provider dedicated to pharmaceutical products.? Since establishment in 2004, the Group has determined to apply global vision to local management, and has introduced a series of pharmaceutical products embedded with technologies that represent international advanced level to China, South America, Eastern European and south Asia countries.? As of Dec 2015, the company had portfolio of pharmaceutical products, covering pain management, cardiovascular, respiratory, gastroenterology, immunology and other therapeutic areas.? At the same time, the Group endeavors to uplift the market value of the
- JiangYin Yuzhe International Trading Co., Ltd IM:
- Zhejiang South Magnetic Industry CO.LTD is specialized in product design of sintered ndfeb permanent magnet materials,Website:http://www.southmagnet.net, the research and development, manufacturing, sales and service of high-tech enterprises.???The company covers an area of 1880 square meters, the existing factory building 9000 square meters.??Power and resources supply condition is superior, convenient raw material supply, has complete advanced production equipment and precision testing instruments and facilities, the company production and sales of various performance, various shapes of ndfeb rare earth permanent magnet products, and can according to customer needs, making all kinds of shapes and specifications of the magnetic material products and related components. Capable of producin
- TAIZHOU JINXIN INDUSTRY & TRADE CO.,LTD:
- Founded by our president Mr.Lin Wenjin in 1992,Website:http://www.cn-jxing.com, Taizhou JinXin is an innovator and manufacturer for quality disposable products. Our main products including plastic fork, knife, spoon, coffee stirrer, cutlery set, plate, cup, bowl, serving tray etc. For over 20 years Taizhou JinXin has been supplying the market with quality products in the Party Stores, Supermarkets, Discount Stores, Retail Stores Hotels, Schools, Colleges, Hospitals, Government, Camps, Caterers. Our products fully comply with FDA guidelines and are manufactured under GMPs. We employ a host of quality assurance procedures at each and every stage of the manufacture process, to ensure the highest level of quality throughout. From the moment we receive an order to the moment it's shipped, the
- Henan Kingway Chemicals Co.,LTD.:
- HENAN KINGWAY CHEMICALS CO., Ltd. is a exporter and manufacturer ofCalcium Gluconate. We have dealt in Calcium Gluconate for many years , hope to supply you in the future .
- Passignment Co. Ltd.:
- Assignment was established by Chris and Gordon when the two of us remained as attending college. Chris finished Warwick while Gordon finished Sydney. We simply assisted classmates and buddies with a few essays or dissertation writing at the start. With no plan, we growed up and more and more students found us for acedamic help.In '09, because of the development of orders, We made the decision to setup a studio named Essay SOS and broadened our expert authors team. We found 20 expert authors with perfect academic background from around the globe to reaction to orders expansion.//http://world wide web.3passignment.com/
- Shanghai ye long Industrial Company:
- Shanghai ye lengthy Industrial Company began in 1996, Our items cover a variety,
- Tianjin Weikete Import and Export Co,Ltd:
- Tianjin Weikete Import&Export Co.,Ltd is really a Chinese manufacturer and exporter within the chemicals for a long time,The Organization is focused on organic chemicals and inorganic chemicals, Particularly in soda ash,Caustic soda, formic acidity, titanium dioxide, committed in offering items utilized in Paint, rubber, textile, leather, cleaning, Glass, Food and a number of other leading consumer industries. All our goods are produced by first class equipments with stable quality
- Zhejiang Yuexi Capsule Co., Ltd.:
- Zhejiang Yuexi Capsule Co.,Ltd.Established in 1986,Website:http://www.yxcaps.com,the company has a long history of producing empty capsules.The company has introduced advanced production equipment and test facilities.It can produce stomach dissolve capsules,intestines dissolve capsules,safety capsules and Muslim capsules of size 00#.00#A.00B.0#L.0#.1#.2#.3#.4#.etc. and colors with perfect lettering as per clients' requirement.The company insists on the developing policy,that is "take credit as the root,quality the most importance,clients' satisfaction the base".We have taken an important position in domestic and overseas capsule market.
- Medix Corporation:
- Medix Corporation, Founded in 1991, is really a premier supplier to medical laboratories, hospitals, and doctors offices through the U . s . States. The Medix selection of name medical supplies includes lab items, pharmaceutical drugs, and many general use products. Medix leverages its associations with more than 75 suppliers to provide special prices on its catalog well over 6,000 Items. With more than 17 years experience of the medical supply industry and satisfied clients all around the U . s . States, Medix is thoroughly acquainted with best of luck it sells and helps to ensure that all items are examined and authorized by the Food and drug administration.
- maxi co ltd:
- We max co ltd was created in 2008 is one of the leading producer of most research chemicals ranging from elementary elements to coins metals
- applingpro industrial co.,ltd:
- Ppling Pro Industrial Co,.Ltd is a potential company with 4 years experience , located in Anhui Province . Our open and flexible idea, The great belief management, using its stable marketing network and excellent business status maintain our development for the time being and is constantly on the expand.We specialized in chemicals ,such as Pharmaceutical Intermediates , research chemicals, Reagent Chemicals and so on . Around the premise of great interest we be more conscious of quality. we stand on your benefit , give you the most reliable advice . For the first co-operation , we always suggest our client to take small amount to test our quality .We have an excellent in worldwide trade business, diligent honest professional talent Team, and evolving using the occasions, with "harmony, Te