CAS Search
Related Chemical Product
Buy Chemical NO: 63-05-8
  • Urgent Purchase CAS NO.:63-05-8
  • Please post your buying leads! Our suppliers will contact you later!
  • For suppliers to better understand your request, enter more info here.

* Product Name:
CAS No.:
* Quantity:
 
 Metric Ton     Kilogram    Gram    Pound
* Valid For:
 5 Days    15    1 Month    3 Month    6 Month    1 Year
* Description:

Max 2000 characters.  Please enter detailed description for the product.
* Email:
 

Androst-4-ene-3,17-dione ( CASNO:63-05-8 )

Identification and Related Records
Name:
Androst-4-ene-3,17-dione
CAS Registry number:
63-05-8
Synonyms:
17-Ketotestosterone
3,17-Dioxoandrost-4-ene
4-Androstene-3,17-dione
Androstenedione
Fecundin
NSC 9563
SKF 2170
D4-Androstene-3,17-dione
Androstenedione
4-Androstenedione
EINECS(EC#):
200-554-5
Molecular Formula:
C19H26O2
Molecular Weight:
286.41
Inchi:
InChI=1/C19H26O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h11,14-16H,3-10H2,1-2H3/t14-,15-,16-,18-,19-/m0/s1
Canonical SMILES:
CC12CCC(=O)C=C1CCC3C2CCC4(C3CCC4=O)C
Isomers smiles:
C[C@]12CCC(=O)C=C1CC[C@@H]3[C@@H]2CC[C@]4([C@H]3CCC4=O)C
Chemical and Physical Properties
Appearance:
white to off-white solid
Density:
1.11 g/cm3
Melting Point:
170-173℃
Boiling Point:
431.4 oC at 760 mmHg
Refractive Index:
1.551
Flash Point:
161.1 oC
Solubilities:
Insoluble
Color/Form:
Dimorphous. Needles from acetone; crystals from hexane
Stability:
Stable at normal temperatures and pressures.
HS Code:
29372900
Storage temp:
Keep tightly closed.
Spectral properties:
Specific optical rotation = +191 deg C/D at 30 deg C (alcohol)
UV max = 235 nm
MASS: 62023 (NIST/EPA/MSDC Mass Spectral Data Base, 1990 Version)
IR: 5443 (Coblentz Society Spectral Collection)
UV: 7-847 (Phillip et al., Organic Electronic Spectral Data, John Wiley & Sons, New York)
1H NMR: 9959 (Sadler Research Laboratories Spectral Collection)
13 C NMR: 482 (Johnson and Jankowski, Carbon 13 NMR Spectra, John Wiley & Sons, New York)
Computed Properties:
Molecular Weight:286.40854 [g/mol]
Molecular Formula:C19H26O2
XLogP3:2.7
H-Bond Donor:0
H-Bond Acceptor:2
Rotatable Bond Count:0
Tautomer Count:10
Exact Mass:286.19328
MonoIsotopic Mass:286.19328
Topological Polar Surface Area:34.1
Heavy Atom Count:21
Formal Charge:0
Complexity:546
Isotope Atom Count:0
Defined Atom Stereocenter Count:5
Undefined Atom Stereocenter Count:0
Defined Bond Stereocenter Count:0
Undefined Bond Stereocenter Count:0
Covalently-Bonded Unit Count:1
Feature 3D Acceptor Count:2
Feature 3D Ring Count:4
Effective Rotor Count:1.6
Conformer Sampling RMSD:0.6
CID Conformer Count:1
Safety and Handling
Hazard Codes:
Xn
Risk Statements:
R40
Safety Statements:
22-24/25-36
Safety:
An experimental teratogen. Other experimental reproductive effects. Questionable carcinogen with experimental tumorigenic data. When heated to decomposition it emits acrid smoke and irritating fumes.
Specification:

White to Off-White Solid
usageEng:Testosterone precursor and metabolite with androgenic activity. Controlled substance (anabolic sterid)
Safety Statements:22-24/25-36
22:Do not breathe dust
24/25:Avoid contact with skin and eyes
36:Wear suitable protective clothing
Octanol/Water Partition Coefficient:
log Kow = 2.75
Disposal Methods:
SRP: The most favorable course of action is to use an alternative chemical product with less inherent propensity for occupational exposure or environmental contamination. Recycle any unused portion of the material for its approved use or return it to the manufacturer or supplier. Ultimate disposal of the chemical must consider: the material's impact on air quality; potential migration in soil or water; effects on animal, aquatic, and plant life; and conformance with environmental and public health regulations.
Use and Manufacturing
Use and Manufacturing:
Methods of Manufacturing

Preparation: ... Isolation from adrenal cortex.
Usage:
Testosterone precursor and metabolite with androgenic activity. Controlled substance (anabolic sterid)
Biomedical Effects and Toxicity
Therapeutic Uses:
Testosterone precursor and metabolite with androgenic activity. Controlled substance (anabolic sterid)
Biomedical Effects and Toxicity:
It is not known whether anabolic steroids are distributed into breast milk. /Anabolic Steroids/
Environmental Fate and Exposure Potential
Environmental Fate/Exposure Summary:
TERRESTRIAL FATE: Based on a classification scheme(1), an estimated Koc value of 750(SRC), determined from a log Kow of 2.75(2)and a regression-derived equation(3), indicates that androstenedione is expected to have moderate mobility in soil(SRC). Volatilization of androstenedione from moist soil surfaces is not expected to be an important fate process(SRC) given an estimated Henry's Law constant of 3.7X10-8 atm-cu m/mole(SRC), using a fragment constant estimation method(4). Androstenedione is not expected to volatilize from dry soil surfaces(SRC) based upon an estimated vapor pressure of 1.8X10-6 mm Hg(SRC), determined from a fragment constant method(5). No biodegradation data were available(SRC, 2005).
AQUATIC FATE: Based on a classification scheme(1), an estimated Koc value of 750(SRC), determined from a log Kow of 2.75(2) and a regression-derived equation(3), indicates that androstenedione is expected to adsorb to suspended solids and sediment(SRC). Volatilization from water surfaces is not expected(3) based upon an estimated Henry's Law constant of 3.7X10-8 atm-cu m/mole(SRC), developed using a fragment constant estimation method(4). According to a classification scheme(5), an estimated BCF of 26(SRC), from its log Kow(2) and a regression-derived equation(6), suggests the potential for bioconcentration in aquatic organisms is low(SRC). No biodegradation data were available(SRC, 2005).
ATMOSPHERIC FATE: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), androstenedione, which has an estimated vapor pressure of 1.8X10-6 mm Hg at 25 deg C(SRC), determined from a fragment constant method(2), will exist in both the vapor and particulate phases in the ambient atmosphere. Vapor-phase androstenedione is degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals(SRC); the half-life for this reaction in air is estimated to be 3.5 hours(SRC), calculated from its rate constant of 1.1X10-10 cu cm/molecule-sec at 25 deg C(SRC) that was derived using a structure estimation method(3). Particulate-phase androstenedione may be removed from the air by wet and dry deposition(SRC). Androstenedione does not absorb light at wavelenghts >290 nm(4) and therefore is not expected to be susceptible to direct photolysis(SRC).
Chemical Company
Sanyuan Jinrui Bio-engineering Co., Ltd.:
 
TAIZHOU BOLON PHARMACHEM CO.,LTD.:
Situated in Taizhou, that is boasted for that Condition API Production Base in China, Bolon Pharmachem is really a API and intermediate manufacturer devoted in oncology API and peptide API. Underneath the leadership from the core R&D people, who're sophisticated in oncology API development as PhD in Chinese Academy of Sciences in addition to Canadian came back PhD who's exceptional at peptide synthesis, along with local professional who enjoy fruitful experience of penem series production, we feel our partner will love the cooperation around a R&D oriented company. Furthermore, our primary items includingirinotecan HCl,Entecavir, Glatiramer Acetate,Triptorelin Acetate and Biapenem,ETC,many will get GMP soon Additionally, in thought on further development, we setup devoted laboratory w 
东莞市天翊网络科技有限公司:
 
Yangzhong Deli Medicine Chemical Co., Ltd.:
profile: Yangzhong Deli Medicine Chemical Co., Ltd. handles pesticide sprays, herbicides and pesticide intermediates. We're ISO 9001:2000 licensed. Our items include 3-chloro-4-F series, 2,3,4-trifluoro-series, 2,4,5-trifluoro series, 3,4,5-trifluoro-series and CFCbromobenzene series. our 2,3,4-trifluoro-series includes 2,3,4-trifluoro nitrobenzene, 2,3,4-trifluoro-aniline, 2,3,4-trifluoro bromobenzene, 2,3,4-trifluoro-chlorobenzene and 2,3,4-trifluoroacetic acidity. our 2,3,4-trifluoro nitrobenzene can be used like a pharmaceutical intermediate. 
东莞市天翊网络科技有限公司:
 
Hangzhou Color Powder Coating Equipment Co.,Ltd:
E have advanced production and processing equipment, for example CNC punch press, the overall press,shearing machine, bending machine, CNC milling machines, cnc lathes, precision tiles and other equipment.We've oven ten years experienced engineers that in electronic, mechanical, painting areas .and our salesforce can speak in British, The spanish language, German language for different countries . Our product range from complete powder coating line to powder spray booth ,curing oven , manual Powder coating system , spares for various powder coating gun. At present we exported into more than 100 countries for 6 years ,more and more user choose COLO and Satisfied with COLO .we have agents in different countries ,COLO it's your worldwide partner within the powder coating.//http://world wi 
东莞市天翊网络科技有限公司:
 
Hangzhou GengYang chemical materials co., LTD:
 Hangzhou GengYang chemical materials co., LTD is really a professional supplier in chemical items development, production, sales for that integration of high-tech businesses from 2010. The business's items are broadly utilized in plastics, Food, Cosmetics and medicine and other fields. Our organization insist available on the market is an essential, we always have a very good cooperation wonderful our clients...we following a policy of "enterprising truth-seeking rigorous unity" forever, and constantly blaze new trails, we've got the technology because the core, the products quality as our existence, all clients as goodness, Let&rsquos provide you with using the greatest quality items, and such as the person in our family&rsquos sales service. we're opinion is "base  
petra medical care complex:
 petra medical care complexmay be the one-stop shop where one can buy all of your needs. We're employed in Wholesale &lifier Bulk from last 14 years. Not old on the market but within 14 years we not have any customer whining against us.  Our merchandise is top quality 90% legit. We are offering 100% guaranteed delivery at any cost for our customer satisfaction (Conditions apply). We're delivering our goods in United kingdom, EU, USA.  
东莞市天翊网络科技有限公司:
 
Guangzhou Donghuang Chemical Technology Co, Ltd.:
Hello I'm Felisa profits representitive for Guangzhou Donghuang Chemical Technology Co, Ltd. We are among the top chemicals manufactures and providers for Akzo Nobel, Nippon Fresh paint, BASF SE, PPG Industries etc. large chemical companies on the planet. Our R&D team has successfully develope ethyl 3-ethoxypropionate (same quality with Ester EEP from Dow and Eastman).We also produce high-boiling point solvents (DBE and GDBE), Texanol alcohol ester, pharmaceutical intermediates (such as (r)Ⅰ(+)-1-Phenylethylamine, sodium salt(SVS), 3,4-Ethylenedioxythiophene (EDOT)) ETC. Guangzhou Donghuang Chemical is really a leading Internet supplier, positively supplying a convenient, economical "one-stop shop" for those who buy chemicals recycleables fro 
Cixi Jayu Sealing Materials Co., Ltd:
Cixi Jayu Sealing Materials Co., Ltd is world leader in manufacturing oil & gas industrial seals and valve seals. The company mainly produces the metal ring joint gasket less than 60 inches and also can produce the seal gaskets with maximum size of 60 inches,Website:http://www.china-ring-gaskets.com, which can provide more than 20 different types and materials for customers to choose. Our professional team also can provide solutions according to different conditions. 
沧州盛泰管业有限公司:
 
Xuancheng Jingrui New Material Co., Ltd27368:
Uancheng Jingrui New Material Co., Ltd. is really a leading nanomaterials manufacturer, is an expert in nanotechnology for several years. The mind office and R&D center-Hangzhou Wanjing New Material Co., Ltd. was built-in 2001, locates Hangzhou, Zhejiang. Because of the good attract investment policy, we moved our production base to Xuancheng, Anhui in '09 and established Xuancheng Jingrui New Material Co., Ltd.Nowadays we've created an entire chain of researching, creating, Marketing and after-purchase maintenance.Our primary items include Nanometer Titanium Dioxide, Nanometer plastic dioxide,Nanometer Alumina, Nano Inorganic Antibacterial Agent, Nano ZrO2. That are broadly utilized in it and telecommunication, cosmetic, Plastic,Dope,Coating, textile,rubber,battery area and the like.Besid 
HEBEI ROLL FORMING MACHINRY FACTORY:
 
Hebei Great Industrial Co., Ltd:
?HEBEI GREAT INDUSTRICL CO., Ltd.???locates in Shijiazhuang City, Hebei Province China.? We manufacture and give you the?industrial materials.??Including pigments,?acid,?fertilizers, feed chemicals,builing materials, ?plastic granules and non-ferrous metals,ETC.?? we'd??rich encounters in past years in this subject, now we are among the leading profe ssional company for industrial materials, particularly with fertilizer and recycled plastics. we always research and innovate our items which have high end, our strict qc system let us offer our clients using the top quality items.? Our business develop the friendship, mutual trust and Respect, using the services of BoDo means the peace of mind from the top quality items most abundant in hug 
Shandong Right Fine Chemical Co.,Ltd:
 
Yancheng Jinbiao Chemical Industry Co.,Ltd.:
 
东莞市天翊网络科技有限公司:
 
zhengzhou double vigour chemical product co.,ltd:
Zhengzhou Double Vigour Chemical Product Co.,ltd is established in 2007 ,Situated in Zhengzhou,the province of Henan.It supervises Hebi Double Vigour Rubber Auxiliary Factory,situated in fine chemical park,Hebi City.The organization has greater than 390 employees and several specialists and controlling persons.Our mail items:MBTS(Dm)/mbt(m)TMTDCBS(CZ)TBBS(NS)/DPG/NOBS/ZMBT/ZDEC TMQ (RD)IPPD(4010NA) and 6PPD(4020)