CAS Search
Related Chemical Product
Chemical Product CAS:56-12-24-Aminobutyric Acid

CAS:56-12-2
4-Aminobutyric Acid

  • CAS No:

    56-12-2
  • Name:

    4-Aminobutyric Acid
  • Molecular Formula:

    C4H9NO2
  • Molecular Weight:

    103.1198
Buy Chemical NO: 56-12-2
  • Urgent Purchase CAS NO.:56-12-2
  • Please post your buying leads! Our suppliers will contact you later!
  • For suppliers to better understand your request, enter more info here.

* Product Name:
CAS No.:
* Quantity:
 
 Metric Ton     Kilogram    Gram    Pound
* Valid For:
 5 Days    15    1 Month    3 Month    6 Month    1 Year
* Description:

Max 2000 characters.  Please enter detailed description for the product.
* Email:
 

4-Aminobutyric Acid ( CASNO:56-12-2 )

Identification and Related Records
Name:
4-Aminobutyric Acid
CAS Registry number:
56-12-2
Synonyms:
Butyricacid, 4-amino- (7CI,8CI)
3-Carboxypropylamine
4-Aminobutanoic acid
4-Aminobutyric acid
Aminalon
GABA
Gaballon
Gamarex
Gammalon
Gammalone
Gammar
Gammasol
Mielogen
Mielomade
NSC 27418
NSC 32044
NSC 45460
NSC51295
Oryza GABA Extract HC 90
Pharma-GABA 20S
Pharmagaba
Pharmagaba 20
Pharmagaba 20D
Piperidic acid
Piperidinic acid
g-Aminobutanoic acid
g-Aminobutyric acid
w-Aminobutyric acid
γ-aminobutyric acid
EINECS(EC#):
200-258-6
Molecular Formula:
C4H9NO2
Molecular Weight:
103.1198
Inchi:
InChI=1S/C4H9NO2/c5-3-1-2-4(6)7/h1-3,5H2,(H,6,7)
InChIKey:
BTCSSZJGUNDROE-UHFFFAOYSA-N
Canonical SMILES:
C(CC(=O)O)CN
Chemical and Physical Properties
Appearance:
white to off-white solid
Density:
1.110 ± 0.06 g/cm3
Melting Point:
195-204℃
Boiling Point:
248oC at 760 mmHg
Refractive Index:
1.465
Flash Point:
103.8 oC
Water:
SOLUBLE
Solubilities:
Stability:
Stable under normal temperatures and pressures.
HS Code:
29224995
Storage temp:
Store at RT.
Computed Properties:
Molecular Weight:103.11976 [g/mol]
Molecular Formula:C4H9NO2
XLogP3:-3.2
H-Bond Donor:2
H-Bond Acceptor:3
Rotatable Bond Count:3
Exact Mass:103.063329
MonoIsotopic Mass:103.063329
Topological Polar Surface Area:63.3
Heavy Atom Count:7
Formal Charge:0
Complexity:62.7
Isotope Atom Count:0
Defined Atom Stereocenter Count:0
Undefined Atom Stereocenter Count:0
Defined Bond Stereocenter Count:0
Undefined Bond Stereocenter Count:0
Covalently-Bonded Unit Count:1
Feature 3D Acceptor Count:2
Feature 3D Donor Count:1
Feature 3D Anion Count:1
Feature 3D Cation Count:1
Effective Rotor Count:3
Conformer Sampling RMSD:0.4
CID Conformer Count:20
Safety and Handling
Hazard Codes:
Xi:Irritant
Risk Statements:
R36/37/38
Safety Statements:
S26;S36
Hazard Note:
Irritant
Specification:
The?IUPAC name of this chemical is?4-aminobutanoic acid. With the?CAS registry number 56-12-2,?it is also named as Gammalone.?The product's categorie are?pharmaceutical raw materials; starting raw materials & intermediates; amino acids; biochemistry; non-proteinorganic amino acids; omega-aminocarboxylic acids; omega-functional alkanols, carboxylic acids, amines & halides; amino acids; food additives; GABA. It is?white microcrystalline powder?which is?easily soluble in water, slightly soluble in hot ethanol, insoluble in cold ethanol, ether and benzene. Additionally, this chemical is sealed in the container and stored in the cool and dry place. The other characteristics of this product can be summarized as:?(1)ACD/BCF (pH 5.5): 1; (2)ACD/BCF (pH 7.4): 1; (3)ACD/KOC (pH 5.5): 1; (4)ACD/KOC (pH 7.4): 1; (5)#H bond acceptors: 3; (6)#H bond donors: 3; (7)#Freely Rotating Bonds: 4; (8)Index of Refraction: 1.465; (9)Molar Refractivity: 25.68 cm3; (10)Molar Volume: 92.866 cm3; (11)Polarizability: 10.18×10-24 cm3; (12)Surface Tension: 46.208 dyne/cm; (13)Enthalpy of Vaporization: 53.425 kJ/mol; (14)Boiling Point: 247.985 °C at 760 mmHg; (15)Vapour Pressure: 0.008 mmHg at 25°C; (16)Rotatable Bond Count: 3; (17)Exact Mass: 103.063329; (18)MonoIsotopic Mass: 103.063329; (19)Topological Polar Surface Area: 63.3; (20)Heavy Atom Count: 7; (21)Complexity: 62.7. Preparation of 4-Aminobutyric acid:?It can be obtained by the?ring opening of?pyrrolidone. Digested?quick lime to?lime milk with distilled water,?suction into the hydrolysis reactor,?adding pyrrolidone, heating to 125-130 °C and the?reaction pressure?is maintained at 0.29MPa. Reacting above 10-14h at this temperature. After the reaction, cooling?to 30 °C, filtered, and washed?by distilled water. Adding ammonium bicarbonate to filtrate until no calcium ion detection. Adding?activated carbon?to decolorize?30min at 80 °C.?Evaporated to precipitate crystals at?60 °C. Adding?ethanol, cooling, filtration and?drying, then we can get the product. The?yield?is 85%. Uses of 4-Aminobutyric acid:?It is not only used as pharmaceutical intermediate, but also used in?biochemical research.?And it has effect of lowering blood lipids that can be used in the treatment and prevention of various types of hepatic coma.?In addition,?it reacts with phthalic acid anhydride to get 4-phthalimido-butyric acid.?This reaction needs reagent?Et3N and solvent?toluene?by heating. The reaction time is?2 hours. The yield is 82%.

When you are using this chemical, please be cautious about it as the following:
It is not only harmful by inhalation, in contact with skin and if swallowed,?but also irritating to eyes, respiratory system and skin.?In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.?If you want to contact this product, you must wear suitable protective clothing. People can use the following data to convert to the molecule structure.
1. SMILES:C(CC(=O)O)CN
2.?InChI:InChI=1/C4H9NO2/c5-3-1-2-4(6)7/h1-3,5H2,(H,6,7)?
3.?InChIKey:BTCSSZJGUNDROE-UHFFFAOYAC The following are the toxicity data which has been tested.

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
cat LD50 intravenous 5gm/kg (5000mg/kg) ? Russian Pharmacology and Toxicology Vol. 47, Pg. 205, 1984.
mouse LD50 intraperitoneal 4950mg/kg (4950mg/kg) BEHAVIORAL: GENERAL ANESTHETIC

BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
Archivum Immunologiae et Therapiae Experimentalis. Vol. 13, Pg. 70, 1965.
?
mouse LD50 intravenous 2748mg/kg (2748mg/kg) ? Archives Internationales de Pharmacodynamie et de Therapie. Vol. 145, Pg. 233, 1963.
mouse LD50 oral 12680mg/kg (12680mg/kg) ? Yakugaku Zasshi. Journal of Pharmacy. Vol. 85, Pg. 463, 1965.
mouse LD50 subcutaneous 9210mg/kg (9210mg/kg) ? Yakugaku Zasshi. Journal of Pharmacy. Vol. 85, Pg. 463, 1965.
mouse LD50 unreported 7230mg/kg (7230mg/kg) ? Bitamin. Vol. 25, Pg. 297, 1962.
rabbit LDLo intravenous 2400mg/kg (2400mg/kg) ? Archivum Immunologiae et Therapiae Experimentalis. Vol. 13, Pg. 70, 1965.
rat LD50 intraperitoneal 5400mg/kg (5400mg/kg) BEHAVIORAL: GENERAL ANESTHETIC

BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
Archivum Immunologiae et Therapiae Experimentalis. Vol. 13, Pg. 70, 1965.
?
rat LD50 intravenous > 5gm/kg (5000mg/kg) ? United States Patent Document. Vol. #3380887,
rat LDLo intracrebral 18mg/kg (18mg/kg) ? Biochemical Pharmacology. Vol. 14, Pg. 1901, 1965.
Report:
Reported in EPA TSCA Inventory.
Biomedical Effects and Toxicity
Biological Activity:
Endogenous inhibitory neurotransmitter.
Pharmacological Action:
- Substances used for their pharmacological actions on GABAergic systems. GABAergic agents include agonists, antagonists, degradation or uptake inhibitors, depleters, precursors, and modulators of receptor function.
Chemical Company
DongGuan YuTeng Machinery Technology Co., Ltd:
DongGuan YuTeng Machinery Technology Co., Ltd. Is a modernized,Website:http://www.yutengquiltmachinery.com, high-tech enterprise specializing in "High-Speed Computerized Shuttle (Lock stitch) Multi-Needle Quilting Machine", "High-Speed Computerized Non-Shuttle (Chain stitch) Multi-Needle Quilting Machine", "Computerized Panel Cutter Machine", "Winding Machine", "Roller Machine", "Bobbin Winder Machine". The products are widely used for quilting mattress, garment, bedding, comforters, duvet, handbags and household ornament, Jackets, home textile, pillow covers etc. With strong R&D both in machinery and software, our company focuses on the profound development in production, sales, and Service. 
Jiangsu Faygo Uion Machinery Co., Ltd:
Faygo Plast is a group company,Website:http://www.faygocn.com, which is engaged in research & manufacturing plastic machinery. There are three teams under the group, one is for PET bottle blowing molding machine, one is for plastic extrusion line, and one is for plastic recycling machines. The PET bottle blowing molding machine is the complete new products, and it has 13 national invention patents. With the new integrated design, the movements of bottle blowing only take 2 seconds. The plastic extrusion lines include matured plastic pipe extrusion line, plastic profile/panel extrusion line, plastic sheet extrusion line, wooden plastic extrusion line. The plastic recycling machines include plastic crushing &washing line, plastic granulating line. 
sukahan(weifang)biotechnology co.,ltd:
SUKAHAN (WEIFANG) Bio-Technology Co., Ltd. is registered in Weifang High & New Technology Development Zone of Shandong Province on 18th Feb, 2004 and the attorney is Australian Chinese David Weihua HAN. SUKAHAN is really a high & new technology enterprise identified by Shandong Science and Technology Bureau, advanced enterprise of scientific and technological by Weifang High & New Technology Development Zone, advanced enterprise in presenting foreign intelligence by Weifang Personnel Office, credit and member enterprise by Shandong Credit System, the best credit integrity client by Banking Industry Association in WEIFANG. With patent number ZL2005 1 0135862.6, our organization contain the patent of technology for enhancing pulp bleaching, which won scientific-technological accomplishme 
Tianjin Chilite Chemical Co.,Ltd:
Tianjin Chilite Chemical Co.,ltd is focused on chemical manufacturing business in china. We stock several types of chemicals that is well utilized in the industries of paint, rubber and water remedies,ETC. We spare no efforts for everyone our clients with Consistene quality,competive cost,punctual shipment,strictly after-sales quality trace.Having to pay more focus on customer's benefit,find cheaper solution for those our clients is our organization mission.Companies strictly enforce the "quality first, customers first"corporate policy,stick to honesty,win-win and mutually advantageous business strategy,with outstanding brand,stable quality,win the strust of numerous clients.  
NINGBO WIN CHEM IMP.& EXP.CO.,LTD:
Established in 1996, is a leading buying and selling company in China. We export pharma raw material, Food and Cosmetic Elements, argochemical, industrial chemicals to around the globe. We've 40sales within this market. Almost 80% each one is chemical master. Annual export value achieve USD 30million. Forte: /-1. Professional acquainted with items and producers in china, establish good relationship together 2. Payment period -recognized T/T, L/C, CAD, Delay of payment 30-120days 3. honest and high efficiency  
Australia Janus Zibo Chemical Co.:
 
Tianjin Yi Ming Tengda Chemical Co., Ltd.:
 
Jinan Wedo Industrial Co., Ltd:
Jinan Wedo Industrial Co., Ltd is a large technological difficulty company that is professional to R&D, produce and export pharmaceutical recycleables, Intermediates and fine chemical items. The organization registered the emblem WEDOCHE, that is famous label in pharmaceutical field. WEDOCHEM has large produce bases for pharmaceutical recycleables and intermediates items In Juye city. The factory covers a place in excess of 50,000M2, and greater than 50 teams of large scales reactors are fixed within the factory. Additionally, through cooperation with a few famous colleges, one effective R&D center is made, which is constantly on the develop competitive new production. While extensively growing the domestic sales network, WEDOCHEM energetically explores worldwide marketplaces. WE 
Tiantai Sanxing Chemical Co.,Ltd.:
 
SHENZHEN VIWIPOW ELECTRONICS CO.,LTD:
Shenzhen Viwipow Electronics Co., Ltd is established in 2010. Our factory is located in Longhua District,Website:http://www.charger-viwipow.com, Shenzhen, China. It is with convenient transportation which is near to Hongkong & Macao. Owning more than 200 employers, It is a professional manufacturer of battery charger, rechargeable battery & battery pack and it is dedicated to the products’ research & development, manufacture and sales for many years. Since now, we have been designed our own brand VIWIPOW product for many years, and we have been one of the battery charger manufacturer in China. 
JINHUA COOFIXTOOLS I&E CO.,LTD:
JINHUA COOFIXTOOLS I&E CO.,LTD is one of leading manufacturers and treading company in China's tool industries,Website:http://www.coofixgroup.com, Such as power tools ,cordless tools ,garden tools, air tools, hand tools. Most kind of power tools best sales all over world , such as Electric Drill,ANGLE GRINDER,SCREWDRIVER,IMPACT DRILL ,ELECTRIC PLANER,CUT-OFF MACHINE ,MITER SAW,ROTARL HAMMER,DEMOLITION HAMMER ,ELECTRIC BLOWER ,CIRCULAR SAW 
Dongying hi-tech spring chemical co.,ltd:
 
Xinjiang Hami Hongshan Chemical Co., Ltd:
 
Shenyang Research Institute of Chemical Industry (SYRICI):
 
China Hangzhou Goalreally Import & Export Co.,Ltd:
 
Junan of Shandong Baihui nursery:
 
Wecan Biological Science & Technology Co., Ltd.:
WECAN(weishi) Biological Science & Technology Co., Ltd., being an expert within the integration of micro-capsules and synthetic diet supplements, is specialized in the manufacture of various encapsulization vitamins (Veterans administration.VD3.VE.VK) and unsaturated essential fatty acids(.DHA.AA) in addition to synthetic dietary supplements. We boast top technology with independent ip legal rights, and are outfitted with domestic unequalled production lines of micro-capsules and premix compounds. fraxel treatments, to date the very best way of items with biological activity and Easily oxidized, features secondary microencapsulation underneath the protection of cold and inert gases. Double microencapsulation will keep the status of micro-capsules while solubilizing items, which could make  
DONGYING ZHISHUI CHEMICAL CO.,LTD:
We're DONGYING ZHISHUI CHEMICAL CO., LTD based in Dongying , China. We're person in TradeKey.com since October, 2011. Our business relates to Chemicals industry and we particularly deal inhydrogen peroxide(H2O2). Please find our product particulars below:Appreciate making the effort to undergo our business profile. If you will find any question, inquiry or comments, don't hesitate to call us. 
Hubei Medical Company:
 
Jiangsu Bailey Steel Bridge Co.,Ltd:
Jiangsu Bailey Steel Bridge Co.,ltd http://world wide web.jsbaileybridge.com