CAS Search
Related Chemical Product
Chemical Product CAS:56-12-24-Aminobutyric Acid

CAS:56-12-2
4-Aminobutyric Acid

  • CAS No:

    56-12-2
  • Name:

    4-Aminobutyric Acid
  • Molecular Formula:

    C4H9NO2
  • Molecular Weight:

    103.1198
Buy Chemical NO: 56-12-2
  • Urgent Purchase CAS NO.:56-12-2
  • Please post your buying leads! Our suppliers will contact you later!
  • For suppliers to better understand your request, enter more info here.

* Product Name:
CAS No.:
* Quantity:
 
 Metric Ton     Kilogram    Gram    Pound
* Valid For:
 5 Days    15    1 Month    3 Month    6 Month    1 Year
* Description:

Max 2000 characters.  Please enter detailed description for the product.
* Email:
 

4-Aminobutyric Acid ( CASNO:56-12-2 )

Identification and Related Records
Name:
4-Aminobutyric Acid
CAS Registry number:
56-12-2
Synonyms:
Butyricacid, 4-amino- (7CI,8CI)
3-Carboxypropylamine
4-Aminobutanoic acid
4-Aminobutyric acid
Aminalon
GABA
Gaballon
Gamarex
Gammalon
Gammalone
Gammar
Gammasol
Mielogen
Mielomade
NSC 27418
NSC 32044
NSC 45460
NSC51295
Oryza GABA Extract HC 90
Pharma-GABA 20S
Pharmagaba
Pharmagaba 20
Pharmagaba 20D
Piperidic acid
Piperidinic acid
g-Aminobutanoic acid
g-Aminobutyric acid
w-Aminobutyric acid
γ-aminobutyric acid
EINECS(EC#):
200-258-6
Molecular Formula:
C4H9NO2
Molecular Weight:
103.1198
Inchi:
InChI=1S/C4H9NO2/c5-3-1-2-4(6)7/h1-3,5H2,(H,6,7)
InChIKey:
BTCSSZJGUNDROE-UHFFFAOYSA-N
Canonical SMILES:
C(CC(=O)O)CN
Chemical and Physical Properties
Appearance:
white to off-white solid
Density:
1.110 ± 0.06 g/cm3
Melting Point:
195-204℃
Boiling Point:
248oC at 760 mmHg
Refractive Index:
1.465
Flash Point:
103.8 oC
Water:
SOLUBLE
Solubilities:
Stability:
Stable under normal temperatures and pressures.
HS Code:
29224995
Storage temp:
Store at RT.
Computed Properties:
Molecular Weight:103.11976 [g/mol]
Molecular Formula:C4H9NO2
XLogP3:-3.2
H-Bond Donor:2
H-Bond Acceptor:3
Rotatable Bond Count:3
Exact Mass:103.063329
MonoIsotopic Mass:103.063329
Topological Polar Surface Area:63.3
Heavy Atom Count:7
Formal Charge:0
Complexity:62.7
Isotope Atom Count:0
Defined Atom Stereocenter Count:0
Undefined Atom Stereocenter Count:0
Defined Bond Stereocenter Count:0
Undefined Bond Stereocenter Count:0
Covalently-Bonded Unit Count:1
Feature 3D Acceptor Count:2
Feature 3D Donor Count:1
Feature 3D Anion Count:1
Feature 3D Cation Count:1
Effective Rotor Count:3
Conformer Sampling RMSD:0.4
CID Conformer Count:20
Safety and Handling
Hazard Codes:
Xi:Irritant
Risk Statements:
R36/37/38
Safety Statements:
S26;S36
Hazard Note:
Irritant
Specification:
The?IUPAC name of this chemical is?4-aminobutanoic acid. With the?CAS registry number 56-12-2,?it is also named as Gammalone.?The product's categorie are?pharmaceutical raw materials; starting raw materials & intermediates; amino acids; biochemistry; non-proteinorganic amino acids; omega-aminocarboxylic acids; omega-functional alkanols, carboxylic acids, amines & halides; amino acids; food additives; GABA. It is?white microcrystalline powder?which is?easily soluble in water, slightly soluble in hot ethanol, insoluble in cold ethanol, ether and benzene. Additionally, this chemical is sealed in the container and stored in the cool and dry place. The other characteristics of this product can be summarized as:?(1)ACD/BCF (pH 5.5): 1; (2)ACD/BCF (pH 7.4): 1; (3)ACD/KOC (pH 5.5): 1; (4)ACD/KOC (pH 7.4): 1; (5)#H bond acceptors: 3; (6)#H bond donors: 3; (7)#Freely Rotating Bonds: 4; (8)Index of Refraction: 1.465; (9)Molar Refractivity: 25.68 cm3; (10)Molar Volume: 92.866 cm3; (11)Polarizability: 10.18×10-24 cm3; (12)Surface Tension: 46.208 dyne/cm; (13)Enthalpy of Vaporization: 53.425 kJ/mol; (14)Boiling Point: 247.985 °C at 760 mmHg; (15)Vapour Pressure: 0.008 mmHg at 25°C; (16)Rotatable Bond Count: 3; (17)Exact Mass: 103.063329; (18)MonoIsotopic Mass: 103.063329; (19)Topological Polar Surface Area: 63.3; (20)Heavy Atom Count: 7; (21)Complexity: 62.7. Preparation of 4-Aminobutyric acid:?It can be obtained by the?ring opening of?pyrrolidone. Digested?quick lime to?lime milk with distilled water,?suction into the hydrolysis reactor,?adding pyrrolidone, heating to 125-130 °C and the?reaction pressure?is maintained at 0.29MPa. Reacting above 10-14h at this temperature. After the reaction, cooling?to 30 °C, filtered, and washed?by distilled water. Adding ammonium bicarbonate to filtrate until no calcium ion detection. Adding?activated carbon?to decolorize?30min at 80 °C.?Evaporated to precipitate crystals at?60 °C. Adding?ethanol, cooling, filtration and?drying, then we can get the product. The?yield?is 85%. Uses of 4-Aminobutyric acid:?It is not only used as pharmaceutical intermediate, but also used in?biochemical research.?And it has effect of lowering blood lipids that can be used in the treatment and prevention of various types of hepatic coma.?In addition,?it reacts with phthalic acid anhydride to get 4-phthalimido-butyric acid.?This reaction needs reagent?Et3N and solvent?toluene?by heating. The reaction time is?2 hours. The yield is 82%.

When you are using this chemical, please be cautious about it as the following:
It is not only harmful by inhalation, in contact with skin and if swallowed,?but also irritating to eyes, respiratory system and skin.?In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.?If you want to contact this product, you must wear suitable protective clothing. People can use the following data to convert to the molecule structure.
1. SMILES:C(CC(=O)O)CN
2.?InChI:InChI=1/C4H9NO2/c5-3-1-2-4(6)7/h1-3,5H2,(H,6,7)?
3.?InChIKey:BTCSSZJGUNDROE-UHFFFAOYAC The following are the toxicity data which has been tested.

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
cat LD50 intravenous 5gm/kg (5000mg/kg) ? Russian Pharmacology and Toxicology Vol. 47, Pg. 205, 1984.
mouse LD50 intraperitoneal 4950mg/kg (4950mg/kg) BEHAVIORAL: GENERAL ANESTHETIC

BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
Archivum Immunologiae et Therapiae Experimentalis. Vol. 13, Pg. 70, 1965.
?
mouse LD50 intravenous 2748mg/kg (2748mg/kg) ? Archives Internationales de Pharmacodynamie et de Therapie. Vol. 145, Pg. 233, 1963.
mouse LD50 oral 12680mg/kg (12680mg/kg) ? Yakugaku Zasshi. Journal of Pharmacy. Vol. 85, Pg. 463, 1965.
mouse LD50 subcutaneous 9210mg/kg (9210mg/kg) ? Yakugaku Zasshi. Journal of Pharmacy. Vol. 85, Pg. 463, 1965.
mouse LD50 unreported 7230mg/kg (7230mg/kg) ? Bitamin. Vol. 25, Pg. 297, 1962.
rabbit LDLo intravenous 2400mg/kg (2400mg/kg) ? Archivum Immunologiae et Therapiae Experimentalis. Vol. 13, Pg. 70, 1965.
rat LD50 intraperitoneal 5400mg/kg (5400mg/kg) BEHAVIORAL: GENERAL ANESTHETIC

BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
Archivum Immunologiae et Therapiae Experimentalis. Vol. 13, Pg. 70, 1965.
?
rat LD50 intravenous > 5gm/kg (5000mg/kg) ? United States Patent Document. Vol. #3380887,
rat LDLo intracrebral 18mg/kg (18mg/kg) ? Biochemical Pharmacology. Vol. 14, Pg. 1901, 1965.
Report:
Reported in EPA TSCA Inventory.
Biomedical Effects and Toxicity
Biological Activity:
Endogenous inhibitory neurotransmitter.
Pharmacological Action:
- Substances used for their pharmacological actions on GABAergic systems. GABAergic agents include agonists, antagonists, degradation or uptake inhibitors, depleters, precursors, and modulators of receptor function.
Chemical Company
Nanjing Asian Chemical Co.,Ltd:
 
Hebei zhongao chemicals imp & exp co.ltd:
 
qingdao ruixinda cold and warm Equipment Ltd.:
 
Nanning Chemical Industry Co.Ltd.:
Nanning Chemical Industry Co.Ltd began in June 1998.It's the greatest comprehensive manufacturer of chemicals in Guangxi province and rank one of the top 500 chemical companies of China.The main items include Alkaline-swimming pool water series and fine chemicals series.The business's convenience of caustic soda rankds the ninth in China and first in Southern China. Theoutput of Caustic Soda,Tichloroisocyanuric Acidity,PVC and Pesticide sprays occupies 70% from the total in Guangxi.Nanning Chemical' items cover marketplaces from the whole southern China region in addition to export marketplaces in The United States,Europe and east Asia. 
Wu han Konberd Biotech Co., Ltd.:
WuhanKonberd Biotech Co., Ltd.,located in NationalBioindustry Base inWuhan,is a high-tech enterprise specialized in pharmaceutical raw materials , Intermediates and research chemicals. As professional developers of fine chemicals and intermediates , we've good cooperation relationship with lots of pharmaceutical, Biotech, chemical industry and research institutions around the globe.All fellowships in company have strong academic background and therefore are devoted to supplying chemical services rich in quality and huge discounts. You are warmly welcome to cooperate with us  
Jiangsu Runtai Chemical Co., Ltd:
Jiangsu Runtai Chemical Co., Ltd. is a professional manufacturer in China producing environmental-friendly water-based coating addictive such as Alcohol Ester-12 (Coalescent agent) and RUANTA-Diester (Sales Hot line: 400-688-0003)oily coating addictive like RUANTA-DBE-a type of high boiling point solvent, as well as drier (Sales Hot line: 400-058-0050); plasticizers includingdimethyl phthalate (DMP) anddiethyl phthalate (DEP), Sales Hot line: 400-626-0050. The organization locates in Economic Development Zone of Jiangyan, Jiangsu Province, the Yangtze river delta economic development circle. The organization covers a place of 100,000 square meters and invested on the hundred million yuan by having an annual capacity of 100, 000 tons. We adopted modern high-efficiency catalytic process an 
Taos Chemical Co., Ltd.:
 
Xi'an Taijin Industrial Electrochemical Technology Co., Ltd.:
Xi'an Taijin Industrial Electrochemical Technology Co., Ltd. (TAIJIN) was founded in 1998 under the name of Northwest Institute for Nonferrous Metal Research (Group) and is a customer oriented and technology driven supplier and manufacturer. Taijin Company produces a wide range of dimensionally stable anodes—platinized and mixed metal oxide activated titanium anodes,Website:http://www.taijinanode.com, repairs and recoats used titanium anodes. Apart from cathodic protection titanium anodes, our titanium anodes are also involved in the following fields: noble metal electrowinning, sodium hypochlorite water treatment, seawater electrochlorination, electroplating industry, chlor-alkali industry, etc. Taijin Company is SGS Verification Supplier, Bureau Veritas, ISO 9001, GJB9001A certified. Mo 
Arpadis (China) Co., Ltd.:
profile: Arpadis (China) CO., Ltd. offers a variety of chemical items like intermediates, organic chemicals, agrochemicals, polymers, pharmaceutical drugs and inorganic chemicals. We serve industries for example food, feed, Cosmetics, Detergent, pharmaceutical drugs, textiles, Automotive Rubber and Beverage. Our pharmaceutical drugs include detomidine hcl, Ursodeoxycholic acidity, Trimethyl Orthoformate, Solanesol, Milrinone, cefathiamidine and raltitrexed. We provide phosphorous acidity, sodium hexametap hosphate, metolachlor andturpentine oil/super grade. 
Hangzhou Xinya Petrochemical Co., Ltd.:
We are professional manufacturer of lubricating greases more than 15 years. Our products including Lithium grease,Website:http://www.greasechina.com, high temperature grease, damping grease, special grease, gear grease, automobile grease, etc. And the products approved by TUV Germany, SGS, Reach Europe Union, NSF USA. We are the only private enterprise approved by Ministry of Commerce of the People's Republic of China.Technology assisted from authorities from Chinese PLA army, we are confident to provide you the right and suitable products. Our brand Alens and Faroa are well known and welcomed by our clients, we also providing OEM service for clients all over the world. 
Zhejiang Back Power Electronics Technology Co.:
 
Xi’an Gemei Metal Material Co., Ltd.:
Xi’an Gemei Metal Material Co., Ltd. (GMC) is a high-tech enterprise,Website:http://www.xagmmetal.com, established in 1995 . With a personnel of more than 350 people and over 44000 square meters of manufactured space , which 20% consist of technological staff. Gemei is one of the largest manufactures of Tungsten and Molybdenum products in China. Gemei specializes in R & D and manufacture of Tungsten, Molybdenum and their alloys. Gemei has advanced technologies ,complete machines and equipments . It also has established a set of scientific management system and strict quality control system .In 2003 Gemei is certified an ISO 9001-2008 and ISO14001-2004 enterprise. With about nearly twenty years' expertise in powder metallurgy, Gemei offers a wide range of superior quality produc 
Hebei Leibangsi Import&Export Co.,Ltd:
 
Ningbo Taifno PTFE Plastic Products Co., Ltd.:
Ningbo Taifno PTFE Plastic Products Co., Ltd was established in 2008,Website:http://www.taifno-ptfes.com, it is a professional manufacture of PTFE sealing products. Our main products include: PTFE Sheet/Gasket/Rode/Tube/Envelope Gasket/Film, Expanded PTFE Sheet/Gasket, PTFE Custom Products, Grand Packing, ect. Meanwhile, we could make the Non-Standard PTFE Products at customers’ request. All our products have FDA, ROHS, SGS, MSDS certificates. Through our efforts, the products have applied to many fields, getting good reputations, products have been exported to lots of countries all over the world. “Integrity Service, Win-win Cooperation” , Looking forward to cooperating with you 
Heng Ying Adhesive Co.,Ltd:
 
XUCHANG RUIDA BIOLOGY&TECHNOLOGY CO.,LTD:
 Situated in Xuchang Economic Development Park,Xuchang Rida Bio-Technology Co.,Ltd.likes unique geographic advantage for we're near to Beijing-HK-Macao Expressway,Lannan Expressway and Shiwu Hi-speed Railway.Covering a place of 333,500sqm,Xuchang Ruida Biology Technology Group(limited)Clients are a sizable private individual proprietorship enterprise,and we're mainly involved in the development,trade,and import and export business of coal chemicals,petrochemicals,pharmaceutical intermediates and food chemicals.Thus far,we've acquired a number of honors form government authorities,including "top-50 high growing enterprise within the food industry of Henan province",etc.Our primary items:chemicals include N-Methyl pyrrolidone(NMP), γ-butyrolactone,Dicyclohexylamine, 
Xiamen HuaXuan Gelatin Co., Ltd.:
Xiamen Huaxuan gelatin Co., Ltd. is really a professional manufacturer and trader focusing in most grades gelatin in Xiamen, China. Our factory continues to be established in 1995 and covers a place of 33000m2. We have greater than 80 employees including greater than 10 technocrats. We make use of the high-technology equipment to fabricate gelatin for example edible gelatin, pharmaceutical grade , technical grade gelatin made from fresh skin or bone of pig and Cattle. Our output is much more than 2200 MT each year. Efficient Management, Top quality and huge discounts make us one of the main companies in this subject in Asia. the look and items in our company have loved reliable status in our country and Within the foreign nations. Welcome all of the buddies in your own home and 
wanlong jainzhu zhuangshi youxiangongsi:
 
Shaanxi Huayu Bio-Tech Co.,Ltd:
Shaanxi Huayu Bio-Tech Co.,Ltd (SXHY) is situated in China's most abundant herbal plant life sources region, the registered capital of three million yuan, dedicated to supplying top quality rare phytochemicals and types for R&D reasons, focused on the supply of high-wholesomeness pharmaceutical component separation and purification technological solutions, and has changed into a high-tech company which combines research, production and services around the high end separation and purification of natural pharmaceutical component and chinese medicine reference substance. SXHY has built numerous lab for that separation and purification of natural items for example saponins, flavonoids and Alkaloids, focusing on in the structure options that come with the primary active component of chin 
Xi An YaXin Chemical Co.,Ltd:
We're Xi'An YaXin Chemical Co., Ltd based in Xingtai , China. We're person in TradeKey.com since December, 2011. Our business relates to Chemicals industry and we particularly offer sodium cyanide, Zinc,copper sulfate pentalydrate, and the like.