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Ethanolamine ( CASNO:141-43-5 )

Identification and Related Records
Name:
Ethanolamine
CAS Registry number:
141-43-5
Synonyms:
2-Aminoethanol
2-Hydroxyethylamine
Ethanolamine solution
Ethanolamine Monoethanolamine
olamine
Monoethanolamine
H-Glycinol
EINECS(EC#):
205-483-3
Molecular Formula:
C2H7NO
Molecular Weight:
61.08
Inchi:
InChI=1/C2H7NO/c3-1-2-4/h4H,1-3H2
InChIKey:
HZAXFHJVJLSVMW-UHFFFAOYSA-N
Canonical SMILES:
C(CO)N
Chemical and Physical Properties
Appearance:
clear liquid
Density:
1.012
Melting Point:
10.3℃
Boiling Point:
170℃
Vapour:
0.458mmHg at 25°C
Refractive Index:
1.453-1.455
Flash Point:
85℃
Water:
miscible
Solubilities:
miscible
Color/Form:
Colorless, viscous liquid or solid (below 51 degrees F) ...
Stability:
Stable. Flammable; incompatible with strong oxidizing agents, strong acids. Hygroscopic.
Storage temp:
Store at RT.
Spectral properties:
Index of refraction: 1.4541 at 20 degC/D
IR: 123 (Sadtler Research Laboratories Prism Collection)
UV: 2260 (Absorption Spectra in the UV and visible Regions, Academic Press, New York)
1H NMR: 9143 (Sadtler Research Laboratories Spectral Collection)
MASS: 34160 (NIST/EPA/MSDC Mass Spectral Database, 1990 version)
Raman: 1007 (Sadtler Research Laboratories Spectral Collection)
Computed Properties:
Molecular Weight:61.08308 [g/mol]
Molecular Formula:C2H7NO
XLogP3:-1.3
H-Bond Donor:2
H-Bond Acceptor:2
Rotatable Bond Count:1
Exact Mass:61.052764
MonoIsotopic Mass:61.052764
Topological Polar Surface Area:46.2
Heavy Atom Count:4
Formal Charge:0
Complexity:10
Isotope Atom Count:0
Defined Atom Stereocenter Count:0
Undefined Atom Stereocenter Count:0
Defined Bond Stereocenter Count:0
Undefined Bond Stereocenter Count:0
Covalently-Bonded Unit Count:1
Feature 3D Acceptor Count:1
Feature 3D Donor Count:2
Feature 3D Cation Count:1
Effective Rotor Count:1
Conformer Sampling RMSD:0.4
CID Conformer Count:3
Safety and Handling
Hazard Codes:
C:Corrosive
Risk Statements:
R20/21/22;R34
Safety Statements:
S26;S36/37/39;S45
HazardClass:
8
Safety:
Hazard Codes:?ToxicT?CorrosiveC??
Risk Statements: 20/21/22-34-39/23/24/25-23/24/25-10
R20/21/22: Harmful by inhalation, in contact with skin and if swallowed.?
R34: Causes burns.?
R23/24/25: Toxic by inhalation, in contact with skin and if swallowed.?
R10: Flammable.
Safety Statements: 26-36/37/39-45
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.?
S36/37/39: Wear suitable protective clothing, gloves and eye/face protection.?
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
RIDADR: UN 2924 3/PG 3
WGK Germany: 1
RTECS: KJ5775000
F: 8-10-23
HazardClass: 8
PackingGroup: III
PackingGroup:
III
Sensitive:
Air Sensitive & Hygroscopic
Skin, Eye, and Respiratory Irritations:
Irritating to skin, eyes, respiratory system.
Cleanup Methods:
1. Remove all ignition sources. 2. Ventilate area of spill or leak. 3. If in liquid form, for small quantities, absorb on paper towels. Evaporate in a safe place (such as a fume hood). Allow sufficient time for evaporating vapors to completely clear the hood ductwork. Burn the paper in a suitable location away from combustible materials. Large quantities can be reclaimed or collected and atomized in a suitable combustion chamber equipped with an appropriate effluent gas cleaning device. 4. If in solid form, allow to melt and follow (3) above.
Transport:
UN 2491
Fire Fighting Procedures:
Use water spray, dry chemical "alcohol resistant" foam or carbon dioxide. use water to keep fire-exposed containers cool.
Wear special protective clothing & positive pressure self-contained breathing apparatus.
Fire Potential:
Combustible liquid.
Formulations/Preparations:
GRADE: Technical; NF /National Formulary/
Grades or Purity: NF; 85% (15% water); commercial; 99+%
DOT Emergency Guidelines:
/GUIDE 153: SUBSTANCES - TOXIC AND/OR CORROSIVE (COMBUSTIBLE)/ Health: TOXIC; inhalation, ingestion, or skin contact with material may cause severe injury or death. Contact with molten substance may cause severe burns to skin and eyes. Avoid any skin contact. Effects of contact or inhalation may be delayed. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution. /Ethanolamine; Ethanolamine, solution; Monoethanolamine/
/GUIDE 153: SUBSTANCES - TOXIC AND/OR CORROSIVE (COMBUSTIBLE)/ Fire or Explosion: Combustible material: may burn but does not ignite readily. When heated, vapors may form explosive mixtures with air: indoors, outdoors, and sewers explosion hazards. Those substances designated with a "P" may polymerize explosively when heated or involved in a fire. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated. Runoff may pollute waterways. Substance may be transported in a molten form. /Ethanolamine; Ethanolamine, solution; Monoethanolamine/
/GUIDE 153: SUBSTANCES - TOXIC AND/OR CORROSIVE (COMBUSTIBLE)/ Public Safety: CALL Emergency Response Telephone Number ... . As an immediate precautionary measure, isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids. Keep unauthorized personnel away. Stay upwind. Keep out of low areas. Ventilate enclosed areas. /Ethanolamine; Ethanolamine, solution; Monoethanolamine/
/GUIDE 153: SUBSTANCES - TOXIC AND/OR CORROSIVE (COMBUSTIBLE)/ Protective Clothing: Wear positive pressure self-contained breathing apparatus (SCBA). Wear chemical protective clothing that is specifically recommended by the manufacturer. It may provide little or no thermal protection. Structural firefighters' protective clothing provides limited protection in fire situations ONLY; it is not effective in spill situations where direct contact with the substance is possible. /Ethanolamine; Ethanolamine, solution; Monoethanolamine/
/GUIDE 153: SUBSTANCES - TOXIC AND/OR CORROSIVE (COMBUSTIBLE)/ Evacuation: ... Fire: If tank, rail car or tank truck is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions. /Ethanolamine; Ethanolamine, solution; Monoethanolamine/
/GUIDE 153: SUBSTANCES - TOXIC AND/OR CORROSIVE (COMBUSTIBLE)/ Fire: Small fires: Dry chemical, CO2 or water spray. Large fires: Dry chemical, CO2, alcohol-resistant foam or water spray. Move containers from fire area if you can do it without risk. Dike fire control water for later disposal; do not scatter the material. Fire involving tanks or car/trailer loads: Fight fire from maximum distance or use unmanned hose holders or monitor nozzles. Do not get water inside containers. Cool containers with flooding quantities of water until well after fire is out. Withdraw immediately in case of rising sound from venting safety devices or discoloration of tank. ALWAYS stay away from tanks engulfed in fire. /Ethanolamine; Ethanolamine, solution; Monoethanolamine/
/GUIDE 153: SUBSTANCES - TOXIC AND/OR CORROSIVE (COMBUSTIBLE)/ Spill or Leak: ELIMINATE all ignition sources (no smoking, flares, sparks or flames in immediate area). Do not touch damaged containers or spilled material unless wearing appropriate protective clothing. Stop leak if you can do it without risk. Prevent entry into waterways, sewers, basements or confined areas. Absorb or cover with dry earth, sand or other non-combustible material and transfer to containers. DO NOT GET WATER INSIDE CONTAINERS. /Ethanolamine; Ethanolamine, solution; Monoethanolamine/
/GUIDE 153: SUBSTANCES - TOXIC AND/OR CORROSIVE (COMBUSTIBLE)/ First Aid: Move victim to fresh air. Call 911 or emergency medical service. Give artificial respiration if victim is not breathing. Do not use mouth-to-mouth method if victim ingested or inhaled the substance; give artificial respiration with the aid of a pocket mask equipped with a one-way valve or other proper respiratory medical device. Administer oxygen if breathing is difficult. Remove and isolate contaminated clothing and shoes. In case of contact with substance, immediately flush skin or eyes with running water for at least 20 minutes. For minor skin contact, avoid spreading material on unaffected skin. Keep victim warm and quiet. Effects of exposure (inhalation, ingestion or skin contact) to substance may be delayed. Ensure that medical personnel are aware of the material(s) involved and take precautions to protect themselves. /Ethanolamine; Ethanolamine, solution; Monoethanolamine/
Exposure Standards and Regulations:
Ethanolamine is an indirect food additive for use only as a component of adhesives.
Reactivities and Incompatibilities:
Strong oxidizers, strong acids, iron [Note: May attack copper, brass, and rubber].
Strong alkali. Reacts with oxidizing materials, acids, halogenated hydrocarbons to produce heat. Reacts with iron producing an unstable and pyrophoric complex trisethanolaminoiron.
Mixing acetic acid and 2-aminoethanol in a closed container caused the temperature and pressure to increase. (It was observed when equimolar quantities of 2 chemicals were mixed in a closed container. In some cases the changes were solely vapor pressure effects due to heat of solution.)
Mixing acetic anhydride and 2-aminoethanol in a closed container caused the temperature and pressure to increase. (It was observed when equimolar quantities of 2 chemicals were mixed in a closed container. In some cases the changes were solely vapor pressure effects due to heat of solution.)
Mixing acrolein and 2-aminoethanol in a closed container caused the temperature and pressure to increase. (It was observed when equimolar quantities of 2 chemicals were mixed in a closed container. In some cases the changes were solely vapor pressure effects due to heat of solution.)
Mixing acrylic acid and 2-aminoethanol in a closed container caused the temperature and pressure to increase. (It was observed when equimolar quantities of 2 chemicals were mixed in a closed container. In some cases the changes were solely vapor pressure effects due to heat of solution.)
Mixing acrylonitrile and 2-aminoethanol in a closed container caused the temperature and pressure to increase. (It was observed when equimolar quantities of 2 chemicals were mixed in a closed container. In some cases the changes were solely vapor pressure effects due to heat of solution.)
Mixing 2-aminoethanol and chlorosulfonic acid in a closed container caused the temperature and pressure to increase. (It was observed when equimolar quantities of 2 chemicals were mixed in a closed container. In some cases the changes were solely vapor pressure effects due to heat of solution.)
Mixing 2-aminoethanol and epichlorohydrin in a closed container caused the temperature and pressure to increase. (It was observed when equimolar quantities of 2 chemicals were mixed in a closed container. In some cases the changes were solely vapor pressure effects due to heat of solution.)
Mixing 2-aminoethanol and 36% hydrochloric acid in a closed container caused the temperature and pressure to increase. (It was observed when equimolar quantities of 2 chemicals were mixed in a closed container. In some cases the changes were solely vapor pressure effects due to heat of solution.)
Mixing 2-aminoethanol and 48.7% hydrofluoric acid in a closed container caused the temperature and pressure to increase. (It was observed when equimolar quantities of 2 chemicals were mixed in a closed container. In some cases the changes were solely vapor pressure effects due to heat of solution.)
Mixing 2-aminoethanol and 70% nitric acid in a closed container caused the temperature and pressure to increase. (It was observed when equimolar quantities of 2 chemicals were mixed in a closed container. In some cases the changes were solely vapor pressure effects due to heat of solution.)
Mixing mesityloxide and 2-aminoethanol in a closed container caused the temperature and pressure to increase. (It was observed when equimolar quantities of 2 chemicals were mixed in a closed container. In some cases the changes were solely vapor pressure effects due to heat of solution.)
Mixing 2-aminoethanol and oleum in a closed container caused the temperature and pressure to increase. (It was observed when equimolar quantities of 2 chemicals were mixed in a closed container. In some cases the changes were solely vapor pressure effects due to heat of solution.)
Mixing 2-aminoethanol and propiolactone (BETA-) in a closed container caused the temperature and pressure to increase. (It was observed when equimolar quantities of 2 chemicals were mixed in a closed container. In some cases the changes were solely vapor pressure effects due to heat of solution.)
Mixing 2-aminoethanol and 96% sulfuric acid in a closed container caused the temperature and pressure to increase. (It was observed when equimolar quantities of 2 chemicals were mixed in a closed container. In some cases the changes were solely vapor pressure effects due to heat of solution.)
Mixing 2-aminoethanol and vinyl acetate in a closed container caused the temperature and pressure to increase. (It was observed when equimolar quantities of 2 chemicals were mixed in a closed container. In some cases the changes were solely vapor pressure effects due to heat of solution.)
Other Preventative Measures:
SRP: The scientific literature for the use of contact lenses in industry is conflicting. The benefit or detrimental effects of wearing contact lenses depend not only upon the substance, but also on factors including the form of the substance, characteristics and duration of the exposure, the uses of other eye protection equipment, and the hygiene of the lenses. However, there may be individual substances whose irritating or corrosive properties are such that the wearing of contact lenses would be harmful to the eye. In those specific cases, contact lenses should not be worn. In any event, the usual eye protection equipment should be worn even when contact lenses are in place.
SRP: Local exhaust ventilation should be applied wherever there is an incidence of point source emissions or dispersion of regulated contaminants in the work area. Ventilation control of the contaminant as close to its point of generation is both the most economical and safest method to minimize personnel exposure to airborne contaminants.
The worker should immediately wash the skin when it becomes contaminated.
Work clothing that becomes wet or significantly contaminated should be removed and replaced.
Workers whose clothing may have become contaminated should change into uncontaminated clothing before leaving the work premises.
SRP: Contaminated protective clothing should be segregated in such a manner so that there is no direct personal contact by personnel who handle, dispose, or clean the clothing. Quality assurance to ascertain the completeness of the cleaning procedures should be implemented before the decontaminated protective clothing is returned for reuse by the workers. Contaminated clothing should not be taken home at end of shift, but should remain at employee's place of work for cleaning.
Protective Equipment and Clothing:
Full face shield; goggles; eye wash facility.
Wear special protective clothing & positive pressure self-contained breathing apparatus.
Wear appropriate personal protective clothing to prevent skin contact.
Wear appropriate eye protection to prevent eye contact.
Eyewash fountains should be provided in areas where there is any possibility that workers could be exposed to the substance; this is irrespective of the recommendation involving the wearing of eye protection.
Respirator Recommendations : Up to 30 ppm: (Assigned Protection Factor = 10) Any chemical cartridge respirator with cartridge(s) providing protection against the compound of concern. Substance reported to cause eye irritation or damage; may require eye protection./(Assigned Protection Factor = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted canister providing protection against the compound of concern./(Assigned Protection Factor = 25) Any powered, air-purifying respirator with cartridge(s) providing protection against the compound of concern. Substance reported to cause eye irritation or damage; may require eye protection./(Assigned Protection Factor = 10) Any supplied-air respirator. Substance reported to cause eye irritation or damage; may require eye protection./(Assigned Protection Factor = 50) Any self-contained breathing apparatus with a full facepiece.
Respirator Recommendations : Emergency or planned entry into unknown concentrations or IDLH conditions: (Assigned Protection Factor = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode./(Assigned Protection Factor = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus.
Respirator Recommendations : Escape: (Assigned Protection Factor = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted canister providing protection against the compound of concern/Any appropriate escape-type, self-contained breathing apparatus.
Specification:
? Ethanolamine , with CAS number of 141-43-5, can be called 1-Amino-2-hydroxyethane ; 2-Amino-1-ethanol ; 2-Aminoaethanol ; EPA Pesticide Chemical Code 011601 ; Glycinol (monoethanolamine) ; Monoaethanolamin ; Monoethanolamine .?It can be used in organic synthesis.The extinguishing agent of?Ethanolamine (CAS NO.141-43-5) are dry powder, foam, sand, carbon dioxide, water mist.
Octanol/Water Partition Coefficient:
log Kow = -1.31
Disposal Methods:
SRP: The most favorable course of action is to use an alternative chemical product with less inherent propensity for occupational exposure or environmental contamination. Recycle any unused portion of the material for its approved use or return it to the manufacturer or supplier. Ultimate disposal of the chemical must consider: the material's impact on air quality; potential migration in soil or water; effects on animal, aquatic, and plant life; and conformance with environmental and public health regulations.
/SRP: For small quantities/1. By absorbing it in vermiculite, dry sand, earth or a similar material and disposing in a secured sanitary landfill. 2. By atomizing in a suitable combustion chamber equipped with an appropriate effluent gas cleaning device.
Use and Manufacturing
Use and Manufacturing:
Methods of Manufacturing

France 650574 (1928 to I.G. Farben); Reid, Lewis, US 2373199 (1945 to Sharples)
Prepared on a large scale by ammonolysis of ethylene oxide; also from nitromethane and formaldehyde
U.S. Exports

(1972) 7.4X10+9 G
U.S. Imports

(1972) 1.8X10+10 G
U.S. Production

This chemical is listed as a High Production Volume (HPV) (65FR81686). Chemicals listed as HPV were produced in or imported into the U.S. in >1 million pounds in 1990 and/or 1994. The HPV list is based on the 1990 Inventory Update Rule. (IUR) (40 CFR part 710 subpart B; 51FR21438).
(1972) 3.7X10+10 G
(1975) 3.75X10+10 GRAMS
(1984) 198,274X10+3 LB
(1986) >100 million-500 million pounds
(1988) 2.2X10+8 LB
(1990) >100 million-500 million pounds
(1994) >100 million-500 million pounds
(1998) >100 million-500 million pounds
(2002) >100 million-500 million pounds
Consumption Patterns

APPROXIMATELY 49% IS USED FOR GAS CONDITIONING (SCRUBBING); ESTIMATED CONSUMPTION PATTERN FOR MONO-, DI-, AND TRIETHANOLAMINES TOGETHER IS 37% FOR SYNTHESIS OF SOAPS AND DETERGENTS FOR TEXTILES, TOILET GOODS, METALS, AND OTHER SPECIALTY SURFACTANT USES; 22% FOR GAS CONDITIONING AND PETROLEUM USE; 20% EXPORTED; 5% FOR SYNTHESIS OF MORPHOLINES; 16% FOR MISC APPLICATIONS INCLUDING EMULSION POLISHES AND HERBICIDES (1973)
Sampling Procedures:
A PROCEDURE IS DESCRIBED FOR PERSONNEL OR AREA MONITORING OF ETHANOLAMINE IN AIR. ALKANOLAMINES ARE COLLECTED FROM AIR ON AL2O3 /ALUMINUM TRIOXIDE/ SAMPLING TUBES AND DESORBED WITH AQ 1-OCTANESULFONIC ACID. WATER IS REMOVED VIA LYOPHILIZATION AND THE RESULTING SALTS ARE DERIVATIZED WITH 1-(HEPTAFLUOROBUTYRYL)IMIDAZOLE. [LANGVARDT PW, MELCHER RG; ANAL CHEM 52 (4): 669-71 (1980)] PubMed Abstract
NIOSH Method 3509. Analyte: 2-Aminoethanol. Matrix: Air. Sampler: Impinger (15 ml 2mM hexanesulfonic acid). Flow Rate: 0.5 to 1 l/min: Sample Size: 100 liter. Shipment: Routine. Sample Stability: Stable at least 3 weeks @ 20 deg C.
NIOSH Method 2007. Analyte: 2-Aminoethanol. Matrix: Air. Sampler: Solid sorbent tube (silica gel, 300 mg/150 mg). Flow Rate: 0.01 to 0.2 l/min: Sample Size: 20 liter. Shipment: Routine. Sample Stability: At least 4 weeks @ 25 deg C.
Biomedical Effects and Toxicity
Biomedical Effects and Toxicity:
The excretion rate in men was found to vary between 4.8 and 22.9 mg/day with a mean of 0.162 mg/kg /body weight/. 11 women were observed to excrete larger amounts, varying between 7.7 and 34.9 mg/day with a mean excretion rate of 0.492 mg/kg/day. The excretion rates in animals were approximately, for cats, 0.47 mg/kg/day; for rats, 1.46 mg/kg/day; and for rabbits, 1.0 mg/kg/day. From 6-47% of monoethanolamine administered to rats can be recovered in the urine.
Persistence of low levels of radioactivity in dog whole blood was obtained after admin of (14)C-labeled ethanolamine. Excretion of radioactivity as % of dose in dog urine was 11. After 24 hr total blood radioactivity as % of dose was 1.69.
/Ethanolamine/ is a normal urine constituent in man, excreted at a rate of 5-23 mg/day ... 40 percent of an administered dose is deaminated and excreted as urea.
The skin penetration of 2-aminoethanol was tested in an in vitro model with full thickness skin prepaeations from mice, rats, humans and rabbits. Within 6 hours the following amounts penetrated through whole skin: rat skin 5.98%, mouse skin 16.92%, rabbit skin 8.66%, human skin 0.61%.
Eight hr after ip injection of 0.52 umoles of 14C-ethanolamine in Wistar rats, 11.5% of the injected dose was recovered as 14CO2. At that time, about 50% of the injected radioactivity was found in the liver, and significant amounts (>2% 14C/g tissue) were detected in the spleen and brain. In the liver, >90% of the radioactivity was found in the lipid fraction; in the kidney, spleen and brain, the percent in the lipid fraction was about 60, 30, and 54%, respectively.
Twenty-four hr after dermal application of 14C-ethanolamine to athymic nude mice (4 ug to 1.45 sq cm), 19% of the applied dose was recovered in expired CO2; this value was similar to that obtained after ip injection of ethanolamine. Radioactivity from 14C-ethanolamine was widely distributed in the body, with the highest levels found in the liver (26%) and kidneys (2.2%). Radioactivity was observed in hepatic phospholipids as the ethanolamine, serine, and choline bases, and in proteins and amino acids isolated from liver and skin sections. Urinary excretion included radioactive ethanolamine, urea, glycine, serine, uric acid, and choline. Thus, ethanolamine penetrates mouse skin and may be oxidized to CO2, incorporated into hepatic phospholipids, or metabolized to amino acids.
Twenty-four hr after administration of 14C-ethanolamine to dogs, total radioactivity in the blood was 1.69% of the administered dose. 11% of the dose was excreted in the urine.
The normal excretion rate, determined in 24-hour urine specimens from eight young adult male students, varied between 4.8 and 22.9 mg ethanolamine/day (mean of 0.162 mg/kg body weight/day); females excreted larger amounts, 12.9 to 57 mg/day (mean of 0.492 mg/kg/day).
From 6% to 48% of orally administered ethanolamine was recovered in rat urine in 24 hours on dosages of 3.33 and 53 mg/100 grams body weight, respectively.
Environmental Fate and Exposure Potential
Environmental Fate/Exposure Summary:
TERRESTRIAL FATE: Based on a classification scheme(1), an estimated Koc value of 5(SRC), determined from a log Kow of -1.31(2) and a regression-derived equation(3), indicates that 2-aminoethanol is expected to have very high mobility in soil(SRC). However, the pKa of 2-aminoethanol is 9.50(4), indicating that this compound will primarily exist as a cation in the environment and cations generally adsorb more strongly to soils containing organic carbon and clay than their neutral counterparts(5). Volatilization of 2-aminoethanol from moist soil surfaces is not expected to be an important fate process(SRC) given an estimated Henry's Law constant of 3.2X10-8 atm-cu m/mole(SRC), derived from its vapor pressure, 0.404 mm Hg(6), and assigned value for water solubility of 1.0X10+6 mg/L (miscible)(7). 2-Aminoethanol is not expected to volatilize from dry soil surfaces(SRC) based upon its vapor pressure(6). Using the Closed Bottle, CO2 Evolution, Manometric Respirometry, and MITI tests, 2-aminoethanol exhibited 64.4, 91.4, 83.0, and 71.2% O2 consumption, respectively, after 28 days(8), suggesting biodegradation is an important environmental fate process in soil(SRC).
AQUATIC FATE: Based on a classification scheme(1), an estimated Koc value of 5(SRC), determined from a log Kow of -1.31(2) and a regression-derived equation(3), indicates that 2-aminoethanol is not expected to adsorb to suspended solids and sediment(SRC). However, the pKa of 2-aminoethanol is 9.50(4), indicating that this compound will primarily exist as a cation in the environment and cations generally adsorb more strongly to soils containing organic carbon and clay than their neutral counterparts. 2-Aminoethanol will exist almost entirely as a cation at pH values of 5 to 9 and therefore volatilization from water surfaces is not expected to be an important fate process(5). According to a classification scheme(6), an estimated BCF of 3(SRC), from its log Kow(2) and a regression-derived equation(7), suggests the potential for bioconcentration in aquatic organisms is low(SRC). Using the Closed Bottle, CO2 Evolution, Manometric Respirometry, and MITI tests, 2-aminoethanol exhibited 64.4, 91.4, 83.0, and 71.2% O2 consumption, respectively, after 28 days(8), suggesting biodegradation is an important environmental fate process in water(SRC).
ATMOSPHERIC FATE: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), 2-aminoethanol, which has a vapor pressure of 0.404 mm Hg at 25 deg C(2), is expected to exist solely as a vapor in the ambient atmosphere. Vapor-phase 2-aminoethanol is degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals(SRC); the half-life for this reaction in air is estimated to be 11 hours(SRC), calculated from its rate constant of 3.6X10-11 cu cm/molecule-sec at 25 deg C(SRC) that was derived using a structure estimation method(3). 2-Aminoethanol does not contain chromophores that absorb at wavelengths >290 nm and therefore is not expected to be susceptible to direct photolysis by sunlight(4).
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Zhangjiakou Changxin Chemical Institute:
 
Binhai Weijia Chemical Co., Ltd.:
profile: Binhai Weijia Chemical Co., Ltd. Produces 2,6-dichlorobenzaldehyde, 2,6-dichlorobenzoic acidity, 3-chloro-2-methylaniline and 2,6-dichlorobenzoyl chloride. the2,6-dichlorobenzaldehyde is comparable to white-colored crystalline powder and includes a melting reason for 68.-71.°C. The Three-chloro-2-methylaniline is really a light brown liquid utilized as medium difficulty for pesticide sprays and dyes. 
Shanxi Taikang Biology Technology Co., Ltd.:
profile:Shanxi Taikang Biology Technology Co., Ltd. handles matrine, Tanshinone IIA, Ammothamnine, and Chelerythrine chloride. 
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