CAS Search
Related Chemical Product
Buy Chemical NO: 134-85-0
  • Urgent Purchase CAS NO.:134-85-0
  • Please post your buying leads! Our suppliers will contact you later!
  • For suppliers to better understand your request, enter more info here.

* Product Name:
CAS No.:
* Quantity:
 
 Metric Ton     Kilogram    Gram    Pound
* Valid For:
 5 Days    15    1 Month    3 Month    6 Month    1 Year
* Description:

Max 2000 characters.  Please enter detailed description for the product.
* Email:
 

4-Chlorobenzophenone ( CASNO:134-85-0 )

Identification and Related Records
Name:
4-Chlorobenzophenone
CAS Registry number:
134-85-0
Iupac name:
(4-chlorophenyl)-phenylmethanone
Synonyms:
Benzophenone, 4-chloro- (8CI)
para-Chlorobenzophenone
(4-chlorophenyl)-phenyl-methanone
Benzophenone, 4-chloro-
p-CBP
Methanone, (4-chlorophenyl)phenyl-
4-Chloro-benzophenone
Methanone
EINECS(EC#):
205-160-7
Molecular Formula:
C13H9ClO
Molecular Weight:
216.67
Inchi:
InChI=1/C13H9ClO/c14-12-8-6-11(7-9-12)13(15)10-4-2-1-3-5-10/h1-9H
InChIKey:
UGVRJVHOJNYEHR-UHFFFAOYSA-N
Canonical SMILES:
C1=CC=C(C=C1)C(=O)C2=CC=C(C=C2)Cl
Chemical and Physical Properties
Appearance:
white to off-white crystalline powder
Density:
1.207 g/cm3
Melting Point:
75-77℃
Boiling Point:
195-196℃ (17 torr)
Flash Point:
143℃
Solubilities:
Insoluble
Color/Form:
Needles from alcohol
White to off-white, crystalline powder
Stability:
Stable under normal temperatures and pressures.
Storage temp:
Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Spectral properties:
MAX ABSORPTION (ALCOHOL): 260 NM (LOG E= 4.32)
SADTLER REFERENCE NUMBER: 13913 (IR, PRISM)
IR: 8632 (Sadtler Research Laboratories IR Grating Collection)
UV: 4051 (Sadtler Research Laboratories Spectral Collection)
1H NMR: 3260 (Sadtler Research Laboratories Spectral Collection)
MASS: 40425 (NIST/EPA/MSDC Mass Spectral Database, 1990 Version)
Computed Properties:
Molecular Weight:216.66296 [g/mol]
Molecular Formula:C13H9ClO
XLogP3:4.1
H-Bond Donor:0
H-Bond Acceptor:1
Rotatable Bond Count:2
Exact Mass:216.034193
MonoIsotopic Mass:216.034193
Topological Polar Surface Area:17.1
Heavy Atom Count:15
Formal Charge:0
Complexity:213
Isotope Atom Count:0
Defined Atom Stereocenter Count:0
Undefined Atom Stereocenter Count:0
Defined Bond Stereocenter Count:0
Undefined Bond Stereocenter Count:0
Covalently-Bonded Unit Count:1
Feature 3D Acceptor Count:1
Feature 3D Ring Count:2
Effective Rotor Count:2
Conformer Sampling RMSD:0.6
CID Conformer Count:1
Safety and Handling
Hazard Codes:
C,Xi,Xn
Risk Statements:
R34
Safety Statements:
S24/25
Hazard Note:
Irritant
Safety:
Hazard Codes:?CorrosiveC,IrritantXi,HarmfulXn
Risk Statements: 34-36/37/38-20/21/22
R34:Causes burns.?
R36/37/38:Irritating to eyes, respiratory system and skin.?
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.
Safety Statements: 26-36/37/39-45-24/25-22
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.?
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.?
S24/25:Avoid contact with skin and eyes.?
S22:Do not breathe dust.
RIDADR: UN 3261 8/PG 2
WGK Germany: 2
RTECS: AM5978800
F: 19
Hazard Note: Irritant
Transport:
25kgs
Specification:
??p-Chlorobenzophenone ,?its cas register number is 134-85-0. It also can be called?4-Chlorobenzophenone ; AI3-00705 ;
?Benzophenone, 4-chloro- ; HSDB 2740 ; Methanone, (4-chlorophenyl)phenyl- ; NSC 2872 ; p-CBP ; para-Chlorobenzophenone .?p-Chlorobenzophenone (CAS NO.134-85-0) is a?white to off-white powder.
Octanol/Water Partition Coefficient:
log Kow = 3.79 (est)
Disposal Methods:
SRP: The most favorable course of action is to use an alternative chemical product with less inherent propensity for occupational exposure or environmental contamination. Recycle any unused portion of the material for its approved use or return it to the manufacturer or supplier. Ultimate disposal of the chemical must consider: the material's impact on air quality; potential migration in soil or water; effects on animal, aquatic, and plant life; and conformance with environmental and public health regulations.
Use and Manufacturing
Use and Manufacturing:
Methods of Manufacturing

4-Chlorobenzophenone is routinely prepared by employing 4-chlorobenzoyl chloride and benzene with AlCl3 as catalyst.
Biomedical Effects and Toxicity
Biomedical Effects and Toxicity:
The metabolism of clemastine, 2-(2-(1-(4-chlorophenyl)-1-phenylethoxylethyl])-1-methylpyrrolidine, has been studied in three adult male volunteers after a single oral dose of 20 mg as the fumarate. After enzymatic hydrolysis solvent extracts of urine were derivatized with N-methyl-N-trimethylsilyltrifluoroacetamide-ammonium iodide and analysed by gas chromatography-mass spectrometry. The structures of metabolites were determined on the basis of electron impact and chemical ionization mass spectra and the identities of some (e.g. carbinol, 4-chlorobenzophenone and 4-chlorophenylstyrene) were confirmed by use of authentic standards. The principal route of metabolism of clemastine in man involves direct oxidation, O-dealkylation (fission of the ether bond), aromatic hydroxylation, aliphatic oxidation, alcoholic dehydration, and then enzymatic hydrolysis. Of the total amount of metabolites excreted in the urine 35% was carbinol (metabolite M3, major metabolite), 15% was M1, 17% was M2, 11% was M4, 9% was M5, 8% was M6 and 5% was M7. [Ho CM et al; J Pharm Pharmacol 51(1): 53-9 (1999)] PubMed Abstract
Environmental Fate and Exposure Potential
Environmental Fate/Exposure Summary:
TERRESTRIAL FATE: Based on a classification scheme(1), an estimated Koc value of 1,700(SRC), determined from a structure estimation method(2), indicates that 4-chlorobenzophenone is expected to have low mobility in soil(SRC). Volatilization of 4-chlorobenzophenone from moist soil surfaces is expected to be an important fate process(SRC) given an estimated Henry's Law constant of 1.4X10-6 atm-cu m/mole(SRC), using a fragment constant estimation method(3). However, adsorption to soil is expected to attenuate volatilization(SRC). 4-Chlorobenzophenone is not expected to volatilize from dry soil surfaces(SRC) based upon an estimated vapor pressure of 1.1X10-4 mm Hg(SRC), determined from a fragment constant method(4). Biodegradation of 4-chlorobenzophenone in soil is expected to be slow based on 0% degradation of the structurally similar substance benzophenone after 28 days in a screening test using an activated sludge inoculum(5).
AQUATIC FATE: Based on a classification scheme(1), an estimated Koc value of 1,700(SRC), determined from a structure estimation method(2), indicates that 4-chlorobenzophenone is expected to adsorb to suspended solids and sediment(SRC). Volatilization from water surfaces is expected(3) based upon an estimated Henry's Law constant of 1.4X10-6 atm-cu m/mole(SRC), developed using a fragment constant estimation method(4). Using this Henry's Law constant and an estimation method(3), volatilization half-lives for a model river and model lake are 25 days and 278 days, respectively(SRC). According to a classification scheme(5), an estimated BCF of 24(SRC), from an estimated log Kow of 3.79(6) and a regression-derived equation(7), suggests the potential for bioconcentration in aquatic organisms is low(SRC). 4-Chlorobenzophenone absorbs light at 260 nm (UV max)(8) indicating that this substance may undergo direct photolysis in the environment(3). Biodegradation of 4-chlorobenzophenone in water is expected to be slow based on 0% degradation of the structurally similar substance benzophenone after 28 days in a screening test using an activated sludge inoculum(9).
ATMOSPHERIC FATE: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), 4-chlorobenzophenone, which has an estimated vapor pressure of 1.1X10-4 mm Hg at 25 deg C(SRC), determined from a fragment constant method(2), is expected to exist solely as a vapor in the ambient atmosphere. Vapor-phase 4-chlorobenzophenone is degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals(SRC); the half-life for this reaction in air is estimated to be 5.3 days(SRC), calculated from its rate constant of 1.4X10-6 cu cm/molecule-sec at 25 deg C(SRC) that was derived using a structure estimation method(3). 4-Chlorobenzophenone absorbs light at 260 nm (UV max)(4) indicating that this substance may undergo direct photolysis in the environment(5).
Chemical Company
Hubei kangxin Agroindustry Co., ltd:
 
Nipa Biocides.:
 
xuzhou chemical ltd:
XUZHOU RUISHITE CHEMICAL Items CO.,LTD disbursing and exporting of chemical materials .During its first establishment period in nineteen nineties 
BaoDing ZhongBoconveyor belt,idler Industry and Mining Machinery Co., ltd 77623:
Onveyor belt, conveyor machinery integrated enterprise.Like a professional and leading conveyor belt and related add-ons manufacturer, Baoding Zhongbo Industry And Mining Machinery Co., Ltd. accomplished a great status with reliable items, top quality, Competitive Cost and good service. We're offering an extensive selection of conveyor devices and related add-ons relevant in a variety of fields and conditions. Using the coverage of entire China domestic market, we've permeated overseas marketplaces effectively for example Southeast nations, Russia and Nigeria. We feel our abundant global business operation experience and competitive items will without doubt enable us to grow global business quickly. Situated in Daqi Industrial Zone, 40km south of Baoding Town of Hebei Province, there exist 
Liuyang wanli craftworks factory:
Liuyang wanli craftworks factory is located in the hometown of fireworks,Website:http://www.waxtorcheschina.com, Liuyang City, Hunan Province, China. It is a professional production and sales of wax torches factory. Through the steady development in the past, the factory has become a professional and comprehensive enterprise integrating wax torches R&D, production and trading together. Our high standard and professional production wax torch factory which located in taipingqiao town of Liuyang City. As we are a manufacturing factory, this enables us to have direct control over the quality and pass the cost savings onto our customers.Our competitive prices, strict quality control and satisfactory customer service has been recognized by many customers around the world. We welcome customers f 
Keshava Organics Pvt. Ltd.:
 
Guangzhou DuoJinCai international trade Co., Ltd.:
The introduction of foreign advanced glass fiber reinforced cement technology. The main products of glass fiber reinforced cement (GLASS FIBRE REINFORCED CEMENT GRC) using the original technology development and production of cement wall decoration products as decorative beauty: decorative line,Website:http://www.grc-china.com, Luo Mazhu, Chuangtao, Mentao, flowers, flower pots, relief murals canopies and other large projects. The company has a high level of computer designers, designers and experienced installation team, strong. Our aim is to provide high quality products and services to the civilian population. Whether it is European style, or China traditional architectural style, no egg is the classical style of architecture, or modern decorative fashion, we can make your ideas for th 
wanyou industrial co.,ltd:
 
SeeU Intelligent Limited OI:
SeeU intelligent Co., Ltd was set up in 2015. In behavior of the headquarter of China Lonrun Electronics Technology Co (GZ).,Website:http://www.seeuoem.net, Ltd who was founded in 1994. Our company located in the business center of Nansha district, Guangzhou. It is not only the pioneer in the areas of Chinese CCTV cameras, Digital Video Recorder and Smart Home equipment, but also the executor with the proposal of High Definition technology in 24 hours a day. As a national-class high and new technology company in the industry of the video information technology, SeeU applies dozens of invention, industrial design and utility model patents and copyrights of software applications. Especially both “Manual Zoom” and “Dual Automatic Linear Synchronous Focusing” created the new area of world-wil 
SUNDAT (S) PTE LTD:
Agrochemicals supplier 
Xuancheng Jingrui New Material Co., Ltd65589:
Uancheng Jingrui New Material Co., Ltd. is really a leading nanomaterials manufacturer, is an expert in nanotechnology for several years. The mind office and R&D center-Hangzhou Wanjing New Material Co., Ltd. was built-in 2001, locates Hangzhou, Zhejiang. Because of the good attract investment policy, we moved our production base to Xuancheng, Anhui in '09 and established Xuancheng Jingrui New Material Co., Ltd.Nowadays we've created an entire chain of researching, creating, Marketing and after-purchase maintenance.Our primary items include Nanometer Titanium Dioxide, Nanometer plastic dioxide,Nanometer Alumina, Nano Inorganic Antibacterial Agent, Nano ZrO2. That are broadly utilized in it and telecommunication, cosmetic, Plastic,Dope,Coating, textile,rubber,battery area and the like.Besid 
Haihang Industry Co.,Ltd.:
 
Wuhan Yuancheng Gongchuang Technology Co., Ltd..:
 
Zhengzhou Lion Abrasives Co.,Ltd.:
 
kunming chemicals &minerals co.ltd:
 
VICHEMO TECHNOLOGY CO.,LTD:
VICHEMO TECHNOLOGY CO.,LTD concentrates on hi-tech and new technology items and processes. It's developed innovative core technology to make sure the greatest quality in our items. According to huge sales in our items in Europe, south america, Southeast Asia and the relaxation around the globe, We've won a good worldwide status.VICHEMO is really a professional and Experienced manufacturer, exporter who's focused on chemical field for example Fine-chemicals, Organics fluoro-that contains chemicals, pharma intermediates and plating Intermediates ,memory and series synthesis new intermediates.VICHEMO have and Gas chromatography instrument, Varian GC/Mass, HPLC to making certain quality.We attempt quality for survival, belief for cooperation, using the market because the guidance, scientific i 
yangsusan:
 
Shenzhen Asiatop Carnitine Technology Co., Ltd:
Shenzhen Asiatop Carnitine Technology Co., Ltd. Started in 1999 by shenzhen Asiatop Investment Co., Ltd.,Xianning Chemo-tech Industrial Co., Ltd., and ETC. We're a Hi-tech chemicals manufacturing corporation with 20 million RMB inregistered capital.We delicate our full attention on chiral synthesising pharmaceutical intermediates, our items are released to overseas market. a lot of our items are high quality and high optical wholesomeness.We now have two middle scale GMP factory situated in Hunan cost, China, which guarantee us a reliable manufacturing capacity. The majority of our productions are industrial level and Each year, you will see 3~5 new items put in market. Thanks for visiting call us for anything you are looking at. We predict to help you out and your esteemed company later o 
REAP CHEMICAL LTD:
Reap Chemical LTD is a leading producer and supplier for agrochemicals and industrial chemicals in China, with its strategic management and operation in Weifang City, Shandong Province. REAPCHEM headquartered based in London, UK, always obedience to the mission of providing consultation services and innovative solutions of agricultural technology for global customers. REAPCHEM manufacture agrochemical products with top quality. With a fully integrated installed plant, we follow stringent quality controls in the manufacturing process and assure that our product comply with the set standards of this industry. To guarantee all the products and services, There are three business segments for REAPCHEM: ? Insecticides, herbicides, fungicides and all kinds of pesticide products. ? Nitrate-nitro 
SHIJIAZHUANG GREEN BRIDGE TRADING CO., LTD: